Evidence map›Paper›PMID 41732215›Full record

ArticleClinical and translational radiation oncology2026

PACE-NODES: A phase III randomised trial of 5 fraction prostate stereotactic body radiotherapy (SBRT) versus 5 fraction prostate and pelvic nodal SBRT.

Angela Pathmanathan, Suneil Jain, John Staffurth, Stephanie Brown, Stephanie Burnett, Fay H Cafferty, Ananya Choudhury, Monisha Dewan, Peter Hoskin, Ken McBride and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Acute enteritis with pelvic SBRT: Influence of bowel delineation methods.Clinical and translational radiation oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Angela PathmanathanThe Royal Marsden NHS Foundation Trust, London, UK.
Suneil JainQueen's University, Belfast, UK.
John StaffurthVelindre University NHS Trust, UK.
Stephanie BrownThe Institute of Cancer Research, London, UK.
Stephanie BurnettThe Institute of Cancer Research, London, UK.
Fay H CaffertyThe Institute of Cancer Research, London, UK.
Ananya ChoudhuryUniversity of Manchester, Manchester, UK.
Monisha DewanThe Institute of Cancer Research, London, UK.
Peter HoskinUniversity of Manchester, Manchester, UK.
Ken McBrideNorthern Ireland Cancer Research Consumer Forum, UK.
Conor K McGarryQueen's University, Belfast, UK.
Elizabeth MilesRadiotherapy Trials QA Group (RTTQA), UK.
Julia MurrayThe Royal Marsden NHS Foundation Trust, London, UK.
Vedang MurthyTata Memorial Centre, Mumbai, India.
Olivia NaismithThe Royal Marsden NHS Foundation Trust, London, UK.
Yee Pei SongThe Christie NHS Foundation Trust, Manchester, UK.
Isabel SyndikusThe Clatterbridge Cancer Centre, Liverpool, UK.
Alison TreeThe Royal Marsden NHS Foundation Trust, London, UK.
Tim WardNCRI Consumer Forum, London, UK.
Emma HallThe Institute of Cancer Research, London, UK.
Nicholas van AsThe Royal Marsden NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PACE-NODES is a phase III randomised controlled trial for patients with high risk localised prostate cancer, planned for radical radiotherapy with at least 12 months of androgen deprivation therapy, and suitable for stereotactic body radiotherapy (SBRT). Patients are randomised to receive either prostate SBRT (control) or prostate and pelvic nodal SBRT. In both arms, treatment is given in 5 fractions delivered on alternate days over 2 weeks. The aim of the trial is to determine whether prostate and pelvic nodal SBRT can improve outcomes for this patient group compared to prostate SBRT.

Indexed as

Pelvic nodal radiotherapyProstate cancerRandomised controlled trialSBRTStereotactic body radiotherapy

Identifiers

PMID41732215
PMCPMC12925429

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.