Evidence map›Paper›PMID 41732144›Full record

ArticleJournal of hand surgery global online2026

Is Cannabis Dependence Associated with Postoperative Infections in Hand and Wrist Surgeries?

Christopher M Dussik, Jeffrey Coombs, Amy Phan, Yasmine Ghattas, Joseph Ferraro, Constantinos Ketonis

Abstract read
In one paragraph

Article in Journal of hand surgery global online, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christopher M DussikUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Jeffrey CoombsUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Amy PhanUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Yasmine GhattasUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Joseph FerraroUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.
Constantinos KetonisUniversity of Rochester Department of Orthopaedic Surgery, University of Rochester School, Rochester, NY.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Recreational cannabis use has been increasing alongside broader legalization efforts worldwide. Despite this trend, relatively little data exist regarding the impact of cannabis dependence on postoperative complications. This knowledge gap is even more pronounced in the context of hand surgery. This study used a large, multi-institutional database to evaluate perioperative complications following soft-tissue surgical procedures of the hand and wrist in patients with documented cannabis dependence versus nondependent patients. Methods: The TriNetX database was queried to determine the incidence of 90-day perioperative complications following soft-tissue surgical procedures involving the hand and wrist. Complications assessed included postoperative admissions, emergency department visits, superficial soft-tissue infections or wound breakdown, systemic infections, and deep surgical site infections. Propensity score matching was performed to control for potential confounding variables and odds ratios were calculated. Results: We identified 498,150 patients who underwent soft-tissue surgical procedures involving the hand and wrist. Among these, 5,607 patients were diagnosed with preoperative cannabis dependence, whereas 492,543 had no history of preoperative cannabis use. Matched analyses revealed increased odds for superficial wound complications/infections (OR 1.9; 95% confidence interval [CI ]1.6-2.3), postoperative admissions (OR 2.5; 95% CI 1.7-3.6), and emergency department visits (OR 1.8; 95% CI 1.6-2.0). Additionally, there were increased odds of sepsis (OR 2.3; 95% CI 1.5-3.6) and subsequent return to the operating room for deep surgical site infections (OR 2.6; 95% CI 1.6-4.6). Conclusions: Patients with documented cannabis dependence demonstrated higher odds of developing wound complications following hand and wrist soft-tissue surgical procedures. This is accompanied by a higher risk of health care utilization, including readmissions and emergency department visits. Although these findings reflect an association rather than a causal relationship, cannabis dependence may serve as a useful variable in perioperative risk stratification and patient counseling.

Indexed as

CannabisHand and WristInfectionSoft-TissueWound Healing

Identifiers

PMID41732144
PMCPMC12925449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.