Evidence map›Paper›PMID 41732078›Full record

SynthesisClinical oral implants research2026

Patient- and Clinician-Reported Outcomes and Outcome Measures Evaluating Timing of Implant Placement in the Edentulous Maxilla: A Systematic Review of Clinical Studies.

Giuseppe A Romito, Isabella Neme Ribeiro Dos Reis, Mohamed A Hassan, Cristina Cunha Villar, Helena Francisco, Claudio Mendes Pannutti

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giuseppe A RomitoDivision of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-5669-912X
Isabella Neme Ribeiro Dos ReisDivision of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Mohamed A HassanDivision of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.
Cristina Cunha VillarDivision of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-5905-5079
Helena FranciscoDental Research Division, Department of Periodontology and Oral Implantology, Guarulhos University - UNG, Guarulhos, Brazil.
Claudio Mendes PannuttiDivision of Periodontology, Department of Stomatology, School of Dentistry, University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-4181-3975

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo address what patient-reported outcomes (PROs) and clinician-reported outcomes (ClinROs) have been reported, and what measures (PROMs and CROMs) have been used to assess them in clinical studies on the timing of implant placement in the edentulous maxilla? MATERIALS AND

methodsSystematic searches were conducted in five databases to identify longitudinal prospective clinical studies. PROMs, CROMs, and methods were extracted. Risk of bias was assessed based on study design, and outcomes were analyzed descriptively.

resultsThirteen studies were included: 1 randomized controlled trial and 12 case series. Delayed placement was reported in 9 studies, immediate in 2, and both in 2. Regarding PROs, 16 outcomes were identified, including oral health-related quality of life (reported in 53.85%), pain intensity (38.46%), satisfaction with the prosthesis (23.08%), postoperative drug use (15.38%), and outcomes related to well-being during surgery, treatment satisfaction, oral health satisfaction, psychosocial impact, daily life impairment and prosthesis functionality, among others (each 7.69%). Eighteen ClinROs were identified. Implant survival was reported in 38.46% of studies, prosthetic complications in 30.77%, and prosthetic survival in 23.08%. Peri-implant health parameters-bone level changes, probing depth, plaque and bleeding indices-were reported in 23.08%. Fewer studies assessed swelling (15.38%), surgical parameters (11.54%), articulation, and oromyofunctional behavior (5.6%). Assessment methods varied widely, limiting comparability. No clear pattern was observed regarding the timing of implant placement.

conclusionsPROs and ClinROs exhibited significant heterogeneity in domains, methods, and reporting. Harmonizing outcome selection and establishing a core outcome set are needed to enhance comparability and reliability.

Indexed as

Dental Implantation, EndosseousDental ImplantsJaw, EdentulousMaxillaOutcome Assessment, Health CarePatient Reported Outcome MeasuresHumansPatient SatisfactionQuality of LifeTime FactorsTreatment OutcomeDental Implantsdental implantedentulousmaxillaoutcome reporting

Identifiers

PMID41732078
PMCPMC12930140

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.