Evidence map›Paper›PMID 41732065›Full record

ArticleClinical oral implants research2026

Consensus Report of Group 1 of the 1st Global Consensus for Clinical Guidelines for the Rehabilitation of the Edentulous Maxilla: Number of Implants, Timing of Implant Placement and Loading.

Nikos Donos, Ethan Ng, Claudio Mendes Pannuti, Giuseppe Alexandre Romito, Helena Cristina Oliveira Francisco, Samir Abou-Ayash, Gustavo Avila-Ortiz, Joao Manuel Mendez Carames, Paolo Casentini, Tali Chackartchi and 18 more

Abstract readConsensus Statement
In one paragraph

Article in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Nikos DonosCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-4117-9073
Ethan NgCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-7538-7866
Claudio Mendes PannutiDepartment of Periodontics, Universidade de São Paulo-USP, School of Dentistry, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-4181-3975
Giuseppe Alexandre RomitoDepartment of Periodontics, Universidade de São Paulo-USP, School of Dentistry, São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-5669-912X
Helena Cristina Oliveira FranciscoInstituto de Implantologia, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-6783-7740
Samir Abou-AyashDepartment of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0003-1047-5571
Gustavo Avila-OrtizDepartment of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-5763-0201
Joao Manuel Mendez CaramesInstituto de Implantologia, Lisbon, Portugal.ORCID https://orcid.org/0000-0002-5544-3744
Paolo CasentiniPrivate Practice, Milan, Italy.
Tali ChackartchiDepartment of Periodontology, Hadassah Medical Center, Faculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.ORCID https://orcid.org/0000-0002-7617-9284
Vivianne ChappuisDepartment of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0003-1227-7587
Stephen ChenMelbourne Dental School, The University of Melbourne, Parkville, Victoria, Australia.
Paul FugazzottoPrivate Practice, Massachusetts, USA.
William V GiannobileDepartment of Oral Medicine, Infection, and Immunity, School of Dental Medicine, Harvard University, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-7102-9746
Yoshiyuki HagiwaraDepartment of Partial Denture Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.ORCID https://orcid.org/0000-0001-6647-7969
Adam HamiltonDepartment of Restorative Dentistry and Biomaterials Sciences, Harvard School of Dental Medicine, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-1523-1904
Saso IvanovskiThe University of Queensland, Center for Orofacial Regeneration, Rehabilitation and Reconstruction (COR3), Brisbane, Queensland, Australia.ORCID https://orcid.org/0000-0001-5339-0936
Sergio KahnSão Leopoldo Mandic, Rio de Janeiro, Rio de Janeiro, Brazil.
Joseph KanDepartment of Implant Dentistry, School of Dentistry, Loma Linda University, Loma Linda, California, USA.ORCID https://orcid.org/0000-0001-5354-638X
France LambertDental Biomaterial Research Unit, University of Liège, Liège, Belgium.ORCID https://orcid.org/0000-0002-1018-2544
Robert Alan LevinePeriodontology and Implantology, Kornberg School of Dentistry, Temple University, Philadelphia, Pennsylvania, USA.
Jose Manuel NavarroDepartment of Periodontology and Implant Dentistry, New York University College of Dentistry, New York, New York, USA.
Turker OrnekolCosmodent Center for Dentistry and Dental Implants, Istanbul, Turkey.
Michael PayerDepartment of Oral Surgery and Orthodontics, University Clinic of Dental Medicine & Oral Health, Medical University of Graz, Graz, Austria.ORCID https://orcid.org/0000-0003-4469-8335
Todd SchoenbaumDepartment of Restorative Sciences, Dental College of Georgia, Augusta University, Augusta, Georgia, USA.ORCID https://orcid.org/0000-0002-2738-5778
Manish Kumar SinghPrivate Practice, Bangalore, India.ORCID https://orcid.org/0000-0002-0116-4328
Sejal ThackerDivision of Periodontology, UConn Health, University of Connecticut School of Dental Medicine, Farmington, Connecticut, USA.
Gil AlcoforadoEgas Moniz School of Health & Science, Egas Moniz Center for Interdisciplinary Research, Almada, Portugal.ORCID https://orcid.org/0000-0002-1545-2267

Funding

European Association for Osseointegration, International Team for Implantology, Osteology Foundation
6 · The paper itself

Abstract

objectivesThe 1st Global Consensus for Clinical Guidelines (GCCG) in Implant Dentistry introduced an innovative, evidence-based approach to developing patient-centered and practical recommendations for the rehabilitation of the edentulous maxilla. Within this framework, Group 1 aimed to formulate clinical recommendations on the number of implants required, timing of implant placement, and timing of loading. MATERIALS AND

methodsGroup 1 followed the S2k-level guideline framework of the Association of the Scientific Medical Societies in Germany (AWMF), using a structured nominal group technique. The evidence base included three systematic reviews evaluating clinician-reported outcomes (ClinROs) and patient-reported outcomes (PROs), supplemented by structured single-round international surveys involving expert clinicians, patients, and cross-disciplinary experts. Survey content covered diagnostics, treatment planning, clinical procedures, and maintenance care. Draft recommendations were discussed during the in-person consensus meeting in Boston (June 16-18, 2025) and finalized through anonymous plenary voting. Consensus was defined as ≥ 75% and ≤ 95% agreement and strong consensus as > 95% agreement.

resultsGroup 1 formulated 12 clinical recommendations across the workflow domains of diagnostic tools, treatment planning, and treatment procedure. During plenary voting, three of these recommendations reached strong consensus, and nine achieved consensus. The number of voters per recommendation ranged from 61 to 90, with an average of 83.

conclusionsThis consensus report provides structured, evidence-based recommendations on implant number, placement timing, and loading protocols for rehabilitation of the edentulous maxilla. These guidelines are intended to support individualized, patient-centered care while also identifying priority areas for future research.

Indexed as

Dental Implantation, EndosseousDental ImplantsJaw, EdentulousMaxillaDental Prosthesis, Implant-SupportedHumansDental Implantsconsensus conferenceedentulous jawfull‐arch restorationimplant overdentureimplant‐supported dental prosthesis

Identifiers

PMID41732065
PMCPMC12930125

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.