Evidence map›Paper›PMID 41731970›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2026

Balloon-Expandable Versus Self-Expanding Valves in Low-Flow, Low-Gradient Aortic Stenosis: Does Valve Type Matter?

Nav Warraich, James A Brown, Abbad Sultan, Dustin Kliner, Derek Serna-Gallegos, Catalin Toma, Amber Makani, Irsa Hasan, Takuya Ogami, Jianhui Zhu and 1 more

Abstract readComparative Study
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Balloon-Expandable Versus Self-Expanding Valves in Low-Flow, Low-Gradient Aortic Stenosis: Does Valve Type Matter?Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nav WarraichDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-9871-1219
James A BrownDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Abbad SultanDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Dustin KlinerHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Derek Serna-GallegosDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Catalin TomaHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0187-2962
Amber MakaniHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Irsa HasanDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Takuya OgamiDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6659-2617
Jianhui ZhuHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Ibrahim SultanDepartment of Cardiothoracic Surgery, Division of Cardiac Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe optimal choice between balloon-expandable (BE) and self-expanding (SE) transcatheter heart valves (THVs) in patients with low-flow low-gradient aortic stenosis (LFLG AS) undergoing transcatheter aortic valve replacement (TAVR) remains unclear.

aimsThis study aims to compare outcomes of BE THVs and SE THVs in patients with LFLG AS.

methodsThis was a retrospective, single-institution cohort study of TAVR procedures between 2012 and 2024. Patients with LFLG AS (mean gradient < 40 mmHg and ejection fraction < 50% or stroke volume index < 35 mL/m

resultsA total of 732 patients identified underwent TAVR for LFLG AS. Of these, 478 (65.3%) received a BE THV and 254 (34.7%) received a SE THV. STS PROM was similar between groups. There was no difference in 30-day mortality between groups. SE THVs had a lower mean gradient but increased rates of paravalvular leak at 30 days post-TAVR. Kaplan-Meier estimates were comparable between groups and there was no significant difference after multivariable analysis (HR 1.15, 95% CI 0.90-1.46, p = 0.27). Cumulative incidence estimates of HF readmission were similar between groups, however, BE THV was associated with reduced hazard of HF readmission on multivariable analysis (HR 0.77, 95% CI 0.59-0.99, p = 0.04).

conclusionsIn patients with LFLG AS undergoing TAVR, BE and SE THVs have comparable midterm survival. BE THVs have a reduced risk of HF readmission on multivariable analysis.

Indexed as

Aortic ValveAortic Valve StenosisBalloon ValvuloplastyHeart Valve ProsthesisHemodynamicsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMalePatient ReadmissionProsthesis DesignRecovery of FunctionRetrospective StudiesRisk Assessmentaortic valve diseaseballoon‐expandablelow‐flow low‐gradient aortic stenosisself‐expandingTAVRtranscatheter aortic valve replacement

Identifiers

PMID41731970
PMCPMC13176724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.