Evidence map›Paper›PMID 41731905›Full record

ArticleThe Journal of physiology2026

Females exhibit greater cardiac volume reductions with expiratory muscle loading during submaximal exercise compared to males.

Sarah A Angus, Michelle Ottlik, Connor J Doherty, Benjamin P Thompson, Jason S Au, Eric J Stöhr, Paolo B Dominelli

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah A AngusDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0003-0265-254X
Michelle OttlikInstitute of Sports Science, COR-HELIX, Leibniz University Hannover, Hannover, Germany.
Connor J DohertyDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0002-4179-9504
Benjamin P ThompsonDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0009-0006-7421-7132
Jason S AuDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0001-8601-323X
Eric J StöhrInstitute of Sports Science, COR-HELIX, Leibniz University Hannover, Hannover, Germany.
Paolo B DominelliDepartment of Kinesiology and Health Sciences, University of Waterloo, Waterloo, ON, Canada.ORCID 0000-0001-5575-4043

Funding

Canada Foundation for Innovation 38432Natural Sciences and Engineering Research Council of Canada RGPIN-2019-04615
6 · The paper itself

Abstract

Intrathoracic pressure (ITP) modulates venous return, ventricular filling and ejection throughout the respiratory cycle, and its fluctuations are accentuated during exercise. We sought to determine whether ITP manipulation during submaximal exercise alters cardiac volumes differently in males and females. Young, healthy participants completed two protocols (both n = 30, 15 females): (i) inspiratory loaded breathing (75 W and 30% W

Indexed as

Cardiac VolumeExerciseExhalationRespiratory MusclesAdultCardiac OutputFemaleHumansMaleStroke VolumeYoung Adultechocardiographyexerciseexpiratory loadingheart‐lung interactionsinspiratory loadingintrathoracic pressuresex differencesstroke volume

Identifiers

PMID41731905
PMCPMC13039240

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.