Evidence map›Paper›PMID 41731681›Full record

SynthesisANZ journal of surgery2026

Surveillance After Pelvic Exenteration: A Systematic Review of Oncological and Functional Follow-Up.

Adrian Hang Yue Siu, Konrad Joseph, Daniel Steffens, Sharon Carey, Michael Solomon, Cherry Koh

Abstract readSystematic Review
In one paragraph

Synthesis in ANZ journal of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adrian Hang Yue SiuSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.ORCID 0000-0001-8151-9805
Konrad JosephDepartment of Family Practice, University of British Columbia, British Columbia, Canada.
Daniel SteffensSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.ORCID 0000-0002-9715-860X
Sharon CareySurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.ORCID 0000-0003-4155-5240
Michael SolomonSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.ORCID 0000-0002-5602-6045
Cherry KohSurgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.ORCID 0000-0003-2547-0204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurveillance following cancer surgery with curative intent serves the purpose of permitting early detection of recurrent disease in addition to monitoring and management of post-resection functional sequelae. Although recommendations exist for most primary cancers, in the context of radical or re-operative surgery such as pelvic exenteration (PE), whether these strategies are appropriate is unclear. The purpose of this review was to evaluate the oncological and functional follow-up strategies after PE.

methodsA comprehensive literature search was conducted across PubMed, Embase, Medline, and Cochrane databases for studies published between January 2000 and December 2024. Eligible studies reported long-term oncological and/or functional follow-up after PE. Studies including other surgical procedures, short-term (< 12 month) follow-up, non-English articles, and case reports were excluded. Data extracted included follow-up length, frequency, and investigation type. Risk of bias was assessed using the AGREE-II and ROBINS-I tools.

resultsForty-two studies were included, comprising 39 cohort studies and three non-original articles. Oncological follow-up, described in 28 studies, frequently included clinic visits every 3-4 months for the first 2-3 years, transitioning to annual reviews after 5 years. Modalities such as tumour markers, CT and MRI imaging, and colonoscopies varied widely. Functional follow-up was addressed in 19 studies, utilising validated instruments including the EORTC QLQ-C30 and SF-36. Most studies lacked standardisation, and no single article comprehensively addressed both oncological and functional aspects.

conclusionCurrent follow-up practices after PE exhibit significant heterogeneity, highlighting the need for standardised protocols. Future research should focus on appropriately sized prospective cohort studies and randomised trials to develop evidence-based guidelines tailored to the unique needs of this high-risk patient population.

Indexed as

Neoplasm Recurrence, LocalPelvic ExenterationFollow-Up StudiesHumanscolorectal cancerfunctional outcomesoncological follow‐uppelvic exenterationpost‐operative surveillancesurvivorship care

Identifiers

PMID41731681
PMCPMC13327584

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.