Evidence map›Paper›PMID 41731529›Full record

ArticleBiotechnology for biofuels and bioproducts2026

Process optimization and transcriptomic profiling reveal an inverse relationship between gene expression and succinic acid production from sugarcane leaves.

Napapat Sitthikitpanya, Nantharat Wongfaed, Sureewan Sittijunda, Sompong O-Thong, Prawit Kongjan, Rattana Jariyaboon, Pensri Plangklang, Alissara Reungsang

Abstract read
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In one paragraph

Article in Biotechnology for biofuels and bioproducts, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Napapat SitthikitpanyaDepartment of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, 40002, Thailand.
Nantharat WongfaedDepartment of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, 40002, Thailand.
Sureewan SittijundaFaculty of Environment and Resource Studies, Mahidol University, Nakhon Pathom, 73170, Thailand.
Sompong O-ThongBiofuel and Biocatalysis Innovation Research Unit, Nakhonsawan Campus, Mahidol University, Nakhonsawan, 60130, Thailand.
Prawit KongjanChemistry Division, Department of Science, Faculty of Science and Technology, Prince of Songkla University, Pattani, 94000, Thailand.
Rattana JariyaboonChemistry Division, Department of Science, Faculty of Science and Technology, Prince of Songkla University, Pattani, 94000, Thailand.
Pensri PlangklangDepartment of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, 40002, Thailand.
Alissara ReungsangDepartment of Biotechnology, Faculty of Technology, Khon Kaen University, Khon Kaen, 40002, Thailand. alissara@kku.ac.th.

Funding

the National Research Council of Thailand (NRCT) No. N42A670487
6 · The paper itself

Abstract

Succinic acid is a valuable platform chemical widely used in the food, pharmaceutical, and bioplastics industries. This study combines process optimization with transcriptomic analysis to investigate succinic acid production from sugarcane leaf hydrolysate (SLH) using Actinobacillus succinogenes TISTR 1994 and to gain insight into the molecular mechanism underlying succinate biosynthesis from SLH-derived sugars. Systematic optimization identified MgCO

Indexed as

Agricultural waste valorizationBioprocess optimizationGene expression–productivity relationshipSuccinic acidTranscriptomics

Identifiers

PMID41731529
PMCPMC13037298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.