Evidence map›Paper›PMID 41731462›Full record

ArticleBMC surgery2026

Endoscopic-assisted transoral atlantoaxial joint release using plasma radiofrequency ablation in management of irreducible atlantoaxial dislocation: a proof-of-concept case series with technical notes.

Zhechen Li, Ruomiao Chen, Rongsheng Chen, Qingcong Zheng, Zhibin Chen, Chuanrong Chen, Weihong Xu

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Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Zhechen Li *Department of Spine Surgery, The First Affiliated Hospital, Fujian Medical University, No.20 Chazhong Road, Taijiang District, Fuzhou, Fujian, 350005, China.
Ruomiao Chen *Department of Plastic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, 350005, China.
Rongsheng Chen *Department of Spine Surgery, The First Affiliated Hospital, Fujian Medical University, No.20 Chazhong Road, Taijiang District, Fuzhou, Fujian, 350005, China.
Qingcong ZhengFujian Medical University, Fuzhou, Fujian, China.
Zhibin ChenFujian Medical University, Fuzhou, Fujian, China.
Chuanrong ChenFujian Medical University, Fuzhou, Fujian, China.
Weihong XuDepartment of Spine Surgery, The First Affiliated Hospital, Fujian Medical University, No.20 Chazhong Road, Taijiang District, Fuzhou, Fujian, 350005, China. xuweihong815@126.com.

Funding

Fujian Provincial Finance Project BPB-2024CRSJoint Funds for the Innovation of Science and Technology, Fujian province No.2021Y9137Nature Science Foundation of Fujian province N0.2025J01089
6 · The paper itself

Abstract

backgroundIrreducible atlantoaxial dislocation (IAAD) is a potentially life-threatening condition and remains surgically challenging. In selected patients, anterior C1-2 release followed by posterior reduction and fusion is effective, but traditional transoral anterior release is technically demanding. Endoscopy and plasma radiofrequency ablation (PRA) may improve visualization and soft tissue handling in a confined corridor, but their combined use for IAAD has been rarely reported. This study aimed to describe an endoscopic-assisted transoral atlantoaxial joint release using PRA and to report preliminary feasibility, procedural safety, and clinical/radiographic outcomes in patients with IAAD.

methodsWe retrospectively reviewed five consecutive patients with IAAD who underwent endoscopic-assisted transoral C1–2 release using PRA, followed by posterior reduction and fusion. Clinical outcomes were assessed with the Japanese Orthopaedic Association (JOA) score and Odom criteria. Radiographic correction was evaluated using the clivus–axial angle (CAA) and cervicomedullary angle (CMA). Perioperative outcomes included operative time, blood loss, airway management, wound healing, and approach-related complications. Fusion was assessed on follow-up computed tomography.

resultsThe mean age was 57.4 years, and the mean follow-up was 33 months. Two patients had restricted mouth opening. Mean total operative time was 229 min (transoral stage 130 min), with a mean estimated blood loss of 170 mL. All patients were extubated in the operating room; none required reintubation, tracheostomy, or intensive care. No cerebrospinal fluid leak, neurological deterioration, posterior pharyngeal wound complication, surgical site infection, dysphagia, or implant-related failure occurred. CAA improved from 117.9° to 143.0°, and CMA improved from 128.5° to 152.9°. Solid fusion was achieved in all cases. JOA scores improved from 8.2 to 14.2, and 80% of patients were rated excellent/good by Odom criteria.

conclusionsThis proof-of-concept series suggests that endoscopic-assisted transoral C1–2 release using PRA can facilitate subsequent posterior reduction and fusion in selected IAAD patients, including those with restricted mouth opening, with encouraging early safety and clinical/radiographic improvement. Given the small retrospective, non-comparative design and the inability to disentangle PRA-related effects from adjunctive drilling, larger multicenter comparative studies are needed to validate these preliminary findings and clarify the specific contribution of PRA within the procedure.

Indexed as

Atlanto-Axial JointEndoscopyJoint DislocationsRadiofrequency AblationAdultAgedFeasibility StudiesFemaleHumansMaleMiddle AgedMouthRetrospective StudiesSpinal FusionTreatment OutcomeCase seriesEndoscopyIrreducible atlantoaxial dislocationPlasma radiofrequency ablationTransoral approach

Identifiers

PMID41731462
PMCPMC13037172

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.