ArticleJournal of perinatology : official journal of the California Perinatal Association2026
The impact of an obstetric substance use screening and biologic testing protocol on neonatal drug testing.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
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Abstract
objectiveSubstance use during pregnancy may affect fetal development and have implications for newborn, childhood, and life-long health. While standardized maternal screening protocols may reduce testing disparities, there are limited data describing the effects of standardized drug screening protocols on neonatal outcomes. STUDY
designWe conducted a retrospective cohort study of deliveries at a tertiary care center during pre-(7/1/2020-6/9/2021) and post-intervention(6/10/2021-5/31/2022) periods around implementation of a standardized obstetric substance use screening/testing protocol. Associations between neonatal testing and maternal race, ethnicity, and insurance status were assessed using generalized estimating equations (SAS 9.4,α = 0.05).
resultAmong 3163 pre-intervention and 3389 post-intervention neonates, testing decreased post-intervention (4.5% vs. 6.2%, p = 0.0035), though a higher proportion lacked corresponding maternal tests (70.8% vs. 32.3%, p < 0.001). Black neonates had higher testing odds, which attenuated after adjusting for insurance status.
conclusionUse of a maternal screening protocol was associated with a reduction in neonatal testing, but disparities persist, warranting further study.
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Registered trials
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