Evidence map›Paper›PMID 41731011›Full record

ArticleNPJ digital medicine2026

A suite of large language models for public health infoveillance.

Xinyu Zhou, Jiaqi Zhou, Chiyu Wang, Qianqian Xie, Kaize Ding, Chengsheng Mao, Yuntian Liu, Zhiyuan Cao, Huangrui Chu, Xi Chen and 3 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinyu Zhou *Division of Biostatistics and Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, 60611, USA.
Jiaqi Zhou *Division of Biostatistics and Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, 60611, USA.
Chiyu WangDepartment of Computer Science, Yale University, New Haven, CT, 06511, USA.
Qianqian XieDepartment of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, 06510, USA.
Kaize DingDepartment of Statistics and Data Science, Northwestern University, Evanston, IL, 60208, USA.
Chengsheng MaoDivision of Biostatistics and Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, 60611, USA.
Yuntian LiuDepartment of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, 06510, USA.
Zhiyuan CaoDepartment of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, 06510, USA.
Huangrui ChuDepartment of Biostatistics, Yale School of Public Health, New Haven, CT, 06510, USA.
Xi ChenDepartment of Health Policy and Management, Yale School of Public Health, New Haven, CT, 06510, USA.
Hua XuDepartment of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, 06510, USA.
Heidi J LarsonDepartment of Infectious Disease Dynamics, London School of Hygiene and Tropical Medicine, London, W1E 7HT, UK.
Yuan LuoDivision of Biostatistics and Informatics, Department of Preventive Medicine, Northwestern University, Chicago, IL, 60611, USA. yuan.luo@northwestern.edu.

Funding

A Life Course Approach to Understanding Racial and Ethnic Disparities in Alzheimer's Disease and Related Dementias and Health CareR01AG077529 · NIA · YALE UNIVERSITY · PI Xi Chen · 2022 to 2026
$3.6M
Modeling the Incompleteness and Biases of Health DataR01LM013337 · NLM · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUO, YUAN · 2020 to 2023
$1.3M
NIA NIH HHS R01 AG077529NIH HHS R01LM013337
6 · The paper itself

Abstract

Social media is a critical platform for understanding and fostering public engagement with health interventions. However, the lack of real-time social media infoveillance on public health issues may lead to delayed responses and suboptimal policy adjustments. To address this gap, we developed PH-LLM-a novel suite of large language models (LLMs) designed for real-time public health monitoring. We curated a multilingual training corpus and trained PH-LLM using QLoRA and LoRA plus, leveraging Qwen 2.5. We constructed a benchmark comprising 19 English and 20 multilingual held-out tasks and evaluated PH-LLM's zero-shot performance. PH-LLM consistently outperformed baseline LLMs of similar and larger sizes. PH-LLM-14B and PH-LLM-32B surpassed Qwen2.5-72B-Instruct, Llama-3.1-70B-Instruct, Mistral-Large-Instruct-2407, and GPT-4o in both English tasks (>=56.0% vs. <= 52.3%) and multilingual tasks (>=59.6% vs. <= 59.1%). PH-LLM represents a significant advancement in real-time public health infoveillance, offering state-of-the-art multilingual capabilities and cost-effective solutions for monitoring public sentiment on health issues.

Identifiers

PMID41731011
PMCPMC13039744

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.