Evidence map›Paper›PMID 41730993›Full record

ArticleScientific reports2026

Potential urine NMR Metabolomic signatures for early diagnosis of paediatric tuberculosis.

Andrea López-Suárez, Patricia Comella-Del-Barrio, Pilar Alonso-Moreno, Yaiza Marín, Palmira Villa-Valverde, Mar Santos-Sebastián, Antoni Noguera-Julian, Anna Gamell, Paula Rodríguez-Molino, Jara Hurtado-Gallego and 9 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Andrea López-Suárez *Pediatric Infectious Diseases Unit, Paediatrics Department, Gregorio Marañón Hospital, Madrid, Spain.
Patricia Comella-Del-Barrio *Pediatric Infectious Diseases Unit, Paediatrics Department, Gregorio Marañón Hospital, Madrid, Spain.
Pilar Alonso-Moreno *NMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Instituto Pluridisciplinar &, Complutense University of Madrid, Madrid, Spain.
Yaiza MarínNMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Instituto Pluridisciplinar &, Complutense University of Madrid, Madrid, Spain.
Palmira Villa-ValverdeNMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Instituto Pluridisciplinar &, Complutense University of Madrid, Madrid, Spain.
Mar Santos-SebastiánPediatric Infectious Diseases Unit, Paediatrics Department, Gregorio Marañón Hospital, Madrid, Spain.
Antoni Noguera-JulianMalalties Infeccioses i Resposta Inflamatòria Sistèmica en Pediatria, Servei d'Infectologia, Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, 08950, Spain.
Anna GamellMalalties Infeccioses i Resposta Inflamatòria Sistèmica en Pediatria, Servei d'Infectologia, Institut de Recerca Pediàtrica Sant Joan de Déu, Barcelona, 08950, Spain.
Paula Rodríguez-MolinoBiomedical Research Centre Network for Infectious Diseases (CIBERINFEC), Carlos III Health Institute, Madrid, Spain.
Jara Hurtado-GallegoBiomedical Research Centre Network for Infectious Diseases (CIBERINFEC), Carlos III Health Institute, Madrid, Spain.
Daniel Blázquez-GameroBiomedical Research Centre Network for Infectious Diseases (CIBERINFEC), Carlos III Health Institute, Madrid, Spain.
Ana Belén Jiménez-JiménezInfectología Pediátrica, Servicio de Pediatría, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.
Adriana NavasInfanta Leonor University Hospital, Madrid, Spain.
Elena Del CastilloBadajoz Maternity and Children's Hospital, Badajoz, Spain.
Marta LlorentePediatric Service, Working group on Respiratory Infections of the Spanish Society of Paediatric Infectious Diseases, Arganda Hospital, Madrid, Spain.
Talía SainzBiomedical Research Centre Network for Infectious Diseases (CIBERINFEC), Carlos III Health Institute, Madrid, Spain.
José DomínguezBiomedical Research Centre Network for Respiratory Diseases (CIBERES), Carlos III Health Institute, Madrid, Spain.
José Luis Izquierdo-GarcíaNMR and Imaging in Biomedicine Group, Department of Chemistry in Pharmaceutical Sciences, Instituto Pluridisciplinar &, Complutense University of Madrid, Madrid, Spain.
Begoña Santiago-GarcíaPediatric Infectious Diseases Unit, Paediatrics Department, Gregorio Marañón Hospital, Madrid, Spain. begona.santiago@salud.madrid.org.

Funding

Comunidad de Madrid Contratos Predoctorales en Formación (PIPF-2022/SAL-GL-24751)".Instituto de Salud Carlos III INT24/0001Instituto de Salud Carlos III (ISCIII) PI17/00711Instituto de Salud Carlos III (ISCIII) PI20/01490Spanish Ministry of Health and Fondos Feder of the EU Contrato Juan Rodés JR24/00015Spanish Ministry of Science and Innovation Juan de la Cierva-Formación postdoctoral fellowship (FJC2021-047271-I)Spanish Ministry of Science and Innovation PID2019-10656RJ-I00Spanish Ministry of Science and Innovation-Instituto de Salud Carlos III and Fondos FEDER Contratos para la intensificación de la actividad investigadora en el Sistema Nacional de Salud, 2023 (INT23/00039)
6 · The paper itself

Abstract

Early diagnosis of tuberculosis (TB) in children is hampered by non-specific symptoms, low bacillary loads, and difficulties in obtaining respiratory samples. We evaluated urinary metabolomics using high-resolution nuclear magnetic resonance (HR-

Indexed as

MetabolomeMetabolomicsTuberculosisAdolescentBiomarkersChildChild, PreschoolEarly DiagnosisFemaleHumansInfantMagnetic Resonance SpectroscopyMaleRetrospective StudiesBiomarkers

Identifiers

PMID41730993
PMCPMC13031401

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.