Evidence map›Paper›PMID 41730791›Full record

ArticleThe Laryngoscope2026

Causal Effect of Air Pollution on Outpatient Visits for Chronic Rhinitis.

Su Hwan Kim, Seong Pyo Kim, Zio Kim, Heung-Woo Park, Jin Youp Kim, Hyung-Jin Yoon

Abstract read
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Su Hwan KimDepartment of Information Statistics, Gyeongsang National University, Jinju, Gyeongsangnamdo, Republic of Korea.
Seong Pyo KimInterdisciplinary Program of Medical Informatics, Seoul National University College of Medicine, Seoul, South Korea.
Zio KimDepartment of Biomedical Engineering, Seoul National University College of Medicine, Seoul, Korea.
Heung-Woo ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Jin Youp KimInterdisciplinary Program of Medical Informatics, Seoul National University College of Medicine, Seoul, South Korea.ORCID 0000-0003-2687-6919
Hyung-Jin YoonInterdisciplinary Program of Medical Informatics, Seoul National University College of Medicine, Seoul, South Korea.ORCID 0000-0003-4432-4894

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAlthough the association between air pollutants and chronic rhinitis has been extensively investigated, causal inference is lacking. We aimed to investigate the causal relationship between air quality index (AQI) and outpatient visits for chronic rhinitis using instrumental variable (IV) analysis, employing thermal inversion.

methodsWe used National Health Insurance Service data collected between January 1, 2014, and December 31, 2017, to determine the short-term causal relationship between air pollution and outpatient visits due to chronic rhinitis. A two-stage generalized method-of-moments Poisson regression model was employed to estimate the causal effects. Stratified analyses by age group and robustness tests for IV with negative controls were conducted.

resultsA total of 81,210,447 outpatient visits for chronic rhinitis were analyzed. IV analysis demonstrated significant positive associations between AQI and outpatient visits on lag days 0, 3, 5, and 6, with the strongest effect observed at Lag 0 (relative risk [RR] 1.078, 95% confidence interval [CI] 1.045-1.113). Stratified analysis revealed that individuals aged 10-19 years were the most vulnerable, showing statistically significant relative risks across all lag days (RR: 1.039-1.161). Analyses using negative control outcomes and exposures supported the validity of the proposed instrumental variable approach, suggesting a robust causal effect of AQI on outpatient visits for chronic rhinitis.

conclusionsWe identified a causal relationship between increased air pollution and outpatient visits for chronic rhinitis. Unlike a simple association potentially confounded by various factors, our analysis provides robust evidence of the causal impact of air pollution on disease burden. LEVEL OF EVIDENCE: 3:

Indexed as

Air PollutantsAir PollutionAmbulatory CareEnvironmental ExposureRhinitisAdolescentAdultAgedChildChild, PreschoolChronic DiseaseFemaleHumansMaleMiddle AgedTaiwanAir Pollutantsair pollutioncausalityrhinitis

Identifiers

PMID41730791
PMCPMC13357243

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.