ArticleCancer medicine2026
Palliative Care Admission at End-of-Life in Liver Cancer: A 10 Year Population-Based Study of 3565 Deaths in Australia.
Article in Cancer medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPalliative care is essential to manage symptoms and end-of-life (EOL) quality, yet its utilisation in liver cancer remains poorly understood. This study examined sociodemographic and clinical characteristics associated with palliative care admission in the last 5 years of life for people with a death from liver cancer.
methodsA population-based retrospective cohort study of adults (≥ 18 years) who died from liver cancer between 2013 and 2022 in New South Wales, Australia was conducted. Multivariable logistic regression identified factors associated with palliative care admissions using linked hospital, cancer registry, notifiable conditions and mortality records.
resultsThere were 3565 deaths and 55.3% of people had at least one palliative care admission. Females (OR 1.25; 95% CI 1.06-1.49), individuals with anxiety-related disorders (OR 1.63; 95% CI 1.18-2.25), drug-related dependence (OR 1.81; 95% CI 1.29-2.54), who lived in rural locations (OR 1.39; 95% CI 1.18-1.64), who had metastatic cancer at diagnosis (OR 1.23; 95% CI 1.01-1.50), who had ≥ 4 hospital admissions (OR 1.43; 95% CI 1.08-1.90) or who died in hospital (OR 4.64; 95% CI 4.64-6.52) had a higher likelihood of a palliative care admission compared to no palliative care admissions. People admitted to intensive care (OR 0.60; 95% CI 0.47-0.75) or who had mechanical ventilation (OR 0.46; 95% CI 0.29-0.74) in the last 12 months prior to EOL were less likely to have a palliative care admission.
conclusionThis is the first Australian study to examine palliative care use in liver cancer on a population-level. Findings support earlier integration of palliative care to reduce high-acuity interventions. These insights have implications for service delivery, equity and policy in EOL care planning.
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