Evidence map›Paper›PMID 41730273›Full record

ArticleCell proliferation2026

Rutin Stabilises β-Catenin Through GSK3β Inhibition to Promote Hair Follicle Regeneration.

Yanyan Zhang, Yuanjie Zhu, Mengyu Jin, Jing Chen, Siqi Yuan, Minjia Yuan, Yuou Sha, Qingmei Liu, Wenyu Wu, Juan Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell proliferation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yanyan ZhangInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
Yuanjie ZhuDepartment of Dermatology, Naval Medical Centre, Naval Medical University, Shanghai, China.
Mengyu JinInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
Jing ChenInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
Siqi YuanInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
Minjia YuanShanghai Qiran Biotechnology Co. Ltd., Shanghai, China.
Yuou ShaDepartment of Dermatology, Huashan Hospital, Shanghai Institute of Dermatology, Fudan University, Shanghai, China.
Qingmei LiuDepartment of Dermatology, Huashan Hospital, Shanghai Institute of Dermatology, Fudan University, Shanghai, China.
Wenyu WuDepartment of Dermatology, Huashan Hospital, Shanghai Institute of Dermatology, Fudan University, Shanghai, China.
Juan WangInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.ORCID https://orcid.org/0000-0003-4440-9302
Xiaolei DingInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.ORCID https://orcid.org/0000-0003-0040-5393

Funding

National Key Research and Development Program of China 2023YFC2509000National Natural Science Foundation of China 82204450National Natural Science Foundation of China 82272278Shanghai Qiran Biotechnology Co. Ltd.
6 · The paper itself

Abstract

Rutin directly binds to GSK3β, stabilising β-catenin and activating Wnt/β-catenin signalling to drive hair cycle.

Indexed as

beta CateninGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaHair FollicleRegenerationRutinAnimalsHumansMiceWnt Signaling Pathwaybeta CateninGlycogen Synthase Kinase 3Glycogen Synthase Kinase 3 betaRutin

Identifiers

PMID41730273
PMCPMC13052294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.