Evidence map›Paper›PMID 41730123›Full record

ArticleAnalytical chemistry2026

NMR Based Real-Time Analysis of Exometabolites Decodes the Mechanism of Action of Antibacterial Molecules, Nanoparticles, and Materials.

Simona Tomaselli, Roberto K Salinas, Michela Alfè, Valentina Gargiulo, Simona Losio, Laura Ragona

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simona TomaselliIstituto di Scienze e Tecnologie Chimiche (SCITEC), CNR, Via A. Corti 12, 20133 Milan, Italy.ORCID 0000-0002-8627-6838
Roberto K SalinasInstitute of Chemistry, University of São Paulo, Av. Prof. Lineu Prestes, 748, 05508-000 São Paulo, Brazil.ORCID 0000-0003-1032-7683
Michela AlfèIstituto di scienze e tecnologie per l'energia e la mobilità sostenibili (STEMS), CNR,Via G. Marconi 4, 80125 Naples, Italy.ORCID 0000-0001-8930-1210
Valentina GargiuloIstituto di scienze e tecnologie per l'energia e la mobilità sostenibili (STEMS), CNR,Via G. Marconi 4, 80125 Naples, Italy.ORCID 0000-0002-6517-2263
Simona LosioIstituto di Scienze e Tecnologie Chimiche (SCITEC), CNR, Via A. Corti 12, 20133 Milan, Italy.ORCID 0000-0003-4333-1523
Laura RagonaIstituto di Scienze e Tecnologie Chimiche (SCITEC), CNR, Via A. Corti 12, 20133 Milan, Italy.ORCID 0000-0003-3893-7117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the mechanism of action of antimicrobial agents is critical for guiding the development of new drugs to overcome antimicrobial resistance. We present a label-free NMR-based approach to characterize the mechanism of action of antibacterial compounds and materials by the analysis of metabolite secretion kinetics. The method (KINEXO, KINetics of EXOmetabolites) is set up using

Indexed as

Anti-Bacterial AgentsEscherichia coliMetal NanoparticlesKineticsMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsSilverStaphylococcus aureusAnti-Bacterial AgentsSilver

Identifiers

PMID41730123
PMCPMC12980489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.