Evidence map›Paper›PMID 41729475›Full record

ArticleJournal of ultrasound2026

Contrast-enhanced ultrasound of renal collecting duct carcinoma: first report of quantitative microvascular characterization with pathologic correlation.

Xueyan Wang, Xiangmin Shen, Chengcheng Niu, Yan Luo, Qinghai Peng, Kui Tang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of ultrasound, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xueyan Wang *Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Xiangmin Shen *Department of Neurology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
Chengcheng NiuDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Yan LuoDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Qinghai PengDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China.
Kui TangDepartment of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, China. tangk20_5@csu.edu.cn.ORCID http://orcid.org/0000-0003-0769-5397

Funding

Natural Science Foundation of Hunan Province 202209042589Natural Science Foundation of Hunan Province 2022JJ70141
6 · The paper itself

Abstract

objectivesTo characterize the contrast-enhanced ultrasound (CEUS) features of collecting duct carcinoma (CDC) with quantitative hemodynamic analysis.

methodsA 28-year-old male with painless hematuria underwent CEUS (SonoVue

resultsCEUS revealed: (1) Heterogeneous arterial enhancement (10 s): Central hyperenhancement (peak SI 37.5%) with peripheral hypoenhancement. (2) Aggressive kinetics: TTP 30 s, wash-out onset 35 s. (3)Absent pseudocapsule sign. Pathology confirmed CDC (Vimentin + /34βE12 + /CK7-/CD10-).

conclusionThis first comprehensive CEUS analysis of CDC demonstrates its unique microvascular phenotype-characterized by abnormal perfusion kinetics and absent pseudocapsule sign correlating with histologic aggressiveness. CEUS enhances CDC diagnosis when combined with immunohistochemistry. ADVANCES IN KNOWLEDGE: This study provides the first quantitative CEUS hemodynamic profile of CDC, identifying a diagnostic triad of heterogeneous enhancement, absent pseudocapsule, and "fast-in-fast-out" kinetics correlating with histologic aggressiveness. We demonstrate that integrating CEUS microvascular phenotyping with immunohistochemistry enhances diagnostic precision for this rare malignancy.

Indexed as

Bellini carcinomaContrast-enhanced ultrasoundRenal collecting duct carcinoma

Identifiers

PMID41729475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.