Evidence map›Paper›PMID 41729292›Full record

ReviewEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Maxillofacial, laryngeal and cervical trauma - how can we do better as the first responder? A 3-step approach for pre-emptive diagnosis and early management.

Hargaven S Gill, Elijah Z Cai, Jia Xu Lim, Raj K Menon, Joseph J H Lee, Owern Low, Jing Tzer Lee, Vigneswaran Nallathamby, Yan Lin Yap, Jane Lim and 1 more

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In one paragraph

Review in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hargaven S GillDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Elijah Z CaiDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Jia Xu LimDivision of Neurosurgery, National Neuroscience Institute (NNI), Singapore, Singapore.
Raj K MenonDivision of General Surgery, National University Hospital (NUH), Singapore, Singapore.
Joseph J H LeeSingapore Civil Defence Force, Singapore, Singapore.
Owern LowDivision of Plastic, Reconstructive and Aesthetic Surgery, Ng Teng Fong General Hospital (NTFGH), Singapore, Singapore.
Jing Tzer LeeDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Vigneswaran NallathambyDivision of Plastic, Reconstructive and Aesthetic Surgery, Ng Teng Fong General Hospital (NTFGH), Singapore, Singapore.
Yan Lin YapDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Jane LimDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore.
Thiam Chye LimDivision of Plastic, Reconstructive and Aesthetic Surgery, National University Hospital (NUH), 5 Lower Kent Ridge Road, Singapore, 119074, Singapore. surlimtc@nus.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConcomitant maxillofacial, laryngeal and cervical spine (MLC) injuries in trauma remains a rare occurrence. It can result in mortality if not diagnosed and managed expeditiously in the field. An algorithm for efficient diagnosis and early management of patients with MLC injuries can be lifesaving.

methodsWe conducted a narrative literature review of PubMed and Cochrane databases and integrated the findings with a retrospective case series of nine consecutive patients with concomitant MLC injuries over a 23-year period at the National University Hospital, Singapore. The primary objective was to develop a simple 3-step prehospital algorithm for early recognition and management of MLC injuries. Secondary objectives were to summarise key red flags and field care bundles for first responders and to describe the patterns, management and outcomes of our case series.

resultsThe literature review highlighted overlapping risk factors, typical injury patterns and high rates of airway-related morbidity and mortality, including reported prehospital death from hypoxia in up to one-third of trauma patients. Delayed or missed diagnoses of cervical spine and laryngeal injuries were also common. In our case series (nine male patients, mean age 47 years), road traffic collision was the dominant mechanism. All patients had maxillofacial, laryngeal and cervical injuries. Six patients required operative fixation of maxillofacial fractures and three required surgical repair and stenting of laryngeal fractures. Based on the literature and local experience, we developed a 3-step algorithm with diagnosis-driven care bundles for prehospital and early emergency department use.

conclusionStrengthening the “chain of survival” through increased prehospital diagnosis of MLC injuries with early intervention has the potential to save lives. The proposed 3-step algorithm offers an accessible framework for paramedics and emergency physicians to improve outcomes in this complex trauma cohort.

Indexed as

Cervical VertebraeEmergency Medical ServicesLarynxMaxillofacial InjuriesMultiple TraumaNeck InjuriesSpinal InjuriesAdultAlgorithmsEarly DiagnosisFemaleHumansMaleMiddle AgedRetrospective StudiesSingaporeCervical traumaField managementLaryngeal traumaMaxillofacialTrauma

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.