Evidence map›Paper›PMID 41729265›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

The effect of time to surgery on clinical outcomes and hospitalization costs in older adults with femoral shaft fractures: A nationwide retrospective cohort study in Japan.

Gaku Gondo, Daisuke Takada, Susumu Kunisawa, Kiyohide Fushimi, Yuichi Imanaka

Abstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimizing discharge planning: predictors of prolonged hospital length of stay after isolated femoral shaft fracture fixation.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gaku GondoDepartment of Healthcare Economics and Quality Management, School of Public Health, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0009-0008-2111-6340
Daisuke TakadaDepartment of Healthcare Economics and Quality Management, School of Public Health, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-9601-7629
Susumu KunisawaDepartment of Healthcare Economics and Quality Management, School of Public Health, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID http://orcid.org/0000-0002-3657-8686
Kiyohide FushimiDepartment of Health Policy and Informatics, Institute of Science Tokyo Graduate School of Medical and Dental Sciences, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1894-0290
Yuichi ImanakaDepartment of Healthcare Economics and Quality Management, School of Public Health, Graduate School of Medicine, Kyoto University, Kyoto, Japan. imanaka-y@umin.net.ORCID http://orcid.org/0000-0003-4613-2159

Funding

Japan Society for the Promotion of Science JP23H00448Ministry of Health, Labour and Welfare JPMH25IA1002
6 · The paper itself

Abstract

purposeThis study aimed to evaluate the effect of early surgery on clinical outcomes and hospitalization costs in older adults with femoral shaft fractures.

methodsWe conducted a retrospective cohort study using a nationwide administrative database in Japan, including patients aged 65 years and over who underwent surgery for femoral shaft fractures between 2014 and 2023. Early surgery was defined as surgery performed on the day of admission or the day after admission. We applied inverse probability of treatment weighting (IPTW) using propensity scores to adjust for confounding. Multiple imputation by chained equations was performed to impute missing data. The primary outcome was in-hospital mortality; secondary outcomes included complications, length of postoperative hospital stay, and hospitalization costs.

resultsAmong 11,087 eligible patients, 3,170 (28.6%) received early surgery. After IPTW adjustment, there was no significant difference in in-hospital mortality (odds ratio (OR), 0.96; 95% confidence interval (CI), 0.66-1.41). However, early surgery was associated with significantly lower odds of pneumonia (OR, 0.64; 95% CI, 0.44-0.94) and urinary tract infection (OR, 0.66; 95% CI, 0.48-0.90), shorter postoperative hospital stay (mean difference, 5.37 days; 95% CI, 3.56-7.19), and reduced hospitalization costs (mean difference, 150,380 Japanese yen; 95% CI, 93,270-207,490).

conclusionEarly surgery for femoral shaft fractures in older adults was not associated with a significant reduction in in-hospital mortality compared to delayed surgery. However, it was associated with fewer complications, shorter postoperative hospital stays, and reduced hospitalization costs. These findings suggest that early surgery may be beneficial for improving postoperative recovery.

Indexed as

Femoral FracturesHospital CostsTime-to-TreatmentAgedAged, 80 and overFemaleHospitalizationHospital MortalityHumansJapanLength of StayMalePostoperative ComplicationsRetrospective StudiesEarly surgeryElderly patientsFemoral shaft fractureMortalityTime to surgery

Identifiers

PMID41729265
PMCPMC12929321

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.