Evidence map›Paper›PMID 41729054›Full record

ArticleCritical care medicine2026

Measuring Uncertainty to Inform Time-Limited Trials: Do We Know What We Don't Know?

Anica C Law, Jacqueline M Kruser

Abstract read
In one paragraph

Article in Critical care medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anica C LawDepartment of Medicine, The Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA.
Jacqueline M KruserDivision of Allergy, Pulmonary, and Critical Care; University of Wisconsin, Madison, WI.ORCID 0000-0003-3258-1869

Funding

Quantifying Uncertainty to Inform Time-Limited Trials of Invasive Mechanical VentilationR01HL179666 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Anica C Law · 2025 to 2026
$1.5M
NHLBI NIH HHS R01 HL179666
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

prognosisprognostic modelingprognostic uncertaintytime-limited trials

Identifiers

PMID41729054
PMCPMC13162135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.