Evidence map›Paper›PMID 41728937›Full record

ArticleJournal of virology2026

Lipidomics reveals the pro-viral roles of ceramides during fish nodavirus infection.

Ya Zhang, Lin Liu, Long Lin, Yin Zhao, Kaitao Xi, Xixi Guo, Qiwei Qin, Xiaohong Huang, Youhua Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ya ZhangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.ORCID 0000-0001-6721-0457
Lin LiuCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Long LinCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Yin ZhaoCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Kaitao XiCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Xixi GuoCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Qiwei QinCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.ORCID 0000-0002-5605-9066
Xiaohong HuangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.ORCID 0000-0001-5655-9960
Youhua HuangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.ORCID 0000-0003-4192-8086

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Red-spotted grouper nervous necrosis virus (RGNNV) is one of the most lethal viral pathogens with high mortality in the fry and juvenile stage of marine fish. Our previous studies demonstrated that RGNNV infection induced the remodeling of intracellular membrane and exploited cellular fatty acid synthesis for infection. However, the roles of lipid metabolism during infection still remained largely uncertain. Here, the global lipidomic profiles of RGNNV in grouper cells were analyzed, and the crucial roles of ceramides during viral infection were investigated. RGNNV significantly altered lipid homeostasis

Indexed as

CeramidesFish DiseasesLipidomicsNodaviridaeRNA Virus InfectionsAnimalsBassCell LineLipid MetabolismVirus ReplicationCeramidesautophagyceramideslipid metabolismpro-viralRGNNV

Identifiers

PMID41728937
PMCPMC13011388

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.