Evidence map›Paper›PMID 41728851›Full record

ArticleACS infectious diseases2026

AntibioticDB: An Updated and Improved Open-Access Database for the Antibacterial Research and Development Community.

Luiza H Galarion, Alan Hennessy, Simon D Harding, Jane F Armstrong, Astrid Pentz-Murr, Jamie A Davies, Alex J O'Neill, Laura J V Piddock

Abstract read
In one paragraph

Article in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luiza H GalarionFaculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0009-0009-5706-0518
Alan HennessyThe Global Antibiotic Research & Development Partnership (GARDP), Geneva 1202, Switzerland.
Simon D HardingInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH8 9XD, U.K.
Jane F ArmstrongInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh EH8 9XD, U.K.ORCID 0000-0002-0524-0260
Astrid Pentz-MurrThe Global Antibiotic Research & Development Partnership (GARDP), Geneva 1202, Switzerland.
Jamie A DaviesEdinburgh Medical School, University of Edinburgh, Edinburgh EH8 9XD, U.K.
Alex J O'NeillFaculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0003-3222-5493
Laura J V PiddockThe Global Antibiotic Research & Development Partnership (GARDP), Geneva 1202, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AntibioticDB (https://www.antibioticdb.com/), originally established in 2017 and since 2021 led by the Global Antibiotic Research & Development Partnership (GARDP), is a freely available database of antibacterial agents to facilitate research and development of new antibacterial therapeutics. Here, we describe a new release of AntibioticDB that has been significantly expanded and updated with the aid of user feedback and which offers additional functionality through a redesigned web portal. Improvements include reciprocal integration with the IUPHAR/BPS Guide to Pharmacology (https://www.guidetopharmacology.org), capturing of compound structure information in the form of standard chemical identifiers (canonical and isomeric SMILES, InChI, and InChI Key), chemical 2D structure images, and harmonizing terminology to optimize database searching. Ongoing curation efforts have increased the number of individual entries to >3,500, a process driven mostly by a significant expansion of historical natural product antibiotics that were previously under-represented in the database. The database is continuously updated by mining the published literature and capturing newly discovered antibacterial compounds as they are reported, making AntibioticDB the most complete global resource on antibacterial agents.

Indexed as

Anti-Bacterial AgentsDatabases, FactualBiocurationDrug DiscoveryHumansInternetAnti-Bacterial AgentsantibacterialantibioticAntibioticDBchemicaldatabasestructure

Identifiers

PMID41728851
PMCPMC12993847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.