Evidence map›Paper›PMID 41728671›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Hydrophilic Janus Micelles From an ABC Triblock Copolymer.

José Muñoz-López, Lei Hu, Hui Wang, Xiaohe Tian, Lorena Ruiz-Pérez, Giuseppe Battaglia

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

José Muñoz-LópezInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Lei HuInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Hui WangSchool of Pharmacy, Wannan Medical College, Wuhu, China.
Xiaohe TianFunctional and Molecular Imaging Key Laboratory of Sichuan Province, Huaxi MR Research Centre (HMRRC), Department of Radiology, and Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy and Cancer Center and National Clinical Research Center For Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Lorena Ruiz-PérezInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Giuseppe BattagliaInstitute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Barcelona, Spain.ORCID https://orcid.org/0000-0003-3349-6770

Funding

Agència de Gestió d'Ajuts Universitaris i de Reserca 2021 SGR 01538Agencia Estatal de Investigación (AEI) and Ministerio de Ciencia e Innovación (MCIN) PID2020-119914RB-I00Agencia Estatal de Investigación (AEI) and Ministerio de Ciencia e Innovación (MCIN) PID2022-138109OB-I00Agencia Estatal de Investigación (AEI) and Ministerio de Ciencia e Innovación (MCIN) PID2023-149206OB-I00Alzheimer's Association Research 23AARG-NTF-1027312European Research Council 101123468European Research Council ERC-2018-CoGCheSSTaG769798European Research Council ERC-2023-PoCNational Key R&D Program of China 2022YFC2009900NextGenerationEU-Biotechnologu Complementary Plan Applied to Health ADNano
6 · The paper itself

Abstract

We describe the creation of an amphiphilic triblock copolymer that drives lateral phase separation within micelle coronas. The design combines a hydrophobic poly(lactide) (PLA) core‑forming block with two distinct hydrophilic segments: poly(ethylene glycol) (PEG) and poly(N‑vinylpyrrolidone) (PVP). In water, the copolymer assembles into spherical micelles, confirmed by cryogenic TEM and multi‑angle light scattering. Selective end‑labelling of PVP with an electron‑dense iridium complex enabled unstained TEM imaging, revealing clear contrast asymmetry that locates PVP to a single hemisphere of the corona. Complementary 2D

Indexed as

amphiphilic copolymersJanus particlespoly(ethylene glycol) (PEG)poly(lactide) (PLA)poly(N‑vinylpyrrolidone) (PVP)

Identifiers

PMID41728671
PMCPMC13023694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.