Evidence map›Paper›PMID 41728649›Full record

ArticleHand (New York, N.Y.)2026

Among Patients Seeking Care for Carpal Tunnel Syndrome, Variation in Symptom Intensity Is Associated More With Variation in Mindsets Than Variation in Compressive Median Neuropathy Severity.

Melle M Broekman, Jacob Thomas, David Ring, Jason R Somogyi, Lee M Reichel, Gregg A Vagner

Abstract read
In one paragraph

Article in Hand (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Melle M BroekmanThe University of Texas at Austin, USA.
Jacob ThomasThe University of Texas at Austin, USA.
David RingThe University of Texas at Austin, USA.ORCID 0000-0002-6506-4879
Jason R SomogyiThe University of Texas at Austin, USA.
Lee M ReichelThe University of Texas at Austin, USA.
Gregg A VagnerThe University of Texas at Austin, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpecialists recognize discordance between levels of discomfort and incapability and pathophysiology severity among people presenting for care of compressive median neuropathy at the carpal tunnel, but there is limited evidence regarding factors associated with this discordance. Using statistical techniques to identify subgroups of mental health factors and pathophysiology factors among people presenting for care of compressive median neuropathy at the carpal tunnel can help determine their relative association with levels of discomfort and incapability. We therefore asked: (1) Can we identify statistical groupings of mental health and pathophysiological factors among people with compressive median neuropathy at the carpal tunnel? and (2) Is there a difference in pain intensity and magnitude of capability among the identified statical groupings?

methodsWe performed a secondary analysis of 150 patients using a

resultsThere were 4 distinct statistical groupings defined by varying levels of fear of painful movement and feelings of distress (anxiety or depression) regarding sensations with minimal variation in mean neuropathy severity. Groupings with greater distress and fear of painful movement had greater mean pain intensity and magnitude of incapability.

conclusionThe evidence that discordance between symptom intensity and compressive median neuropathy severity is accounted for by less healthy mindsets directs clinicians to use relatively notable levels of pain intensity and incapability as a signal to prioritize timely and accurate diagnosis of less healthy mindsets (misconceptions and distress) as a safeguard for comprehensive care.

Indexed as

anxietycarpal tunneldepressionfear of painful movementgroupingsnerve compression

Identifiers

PMID41728649
PMCPMC12929074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.