Evidence map›Paper›PMID 41728600›Full record

ArticleFrontiers in medicine2026

Impacts of neurointerventional therapy combined with intravenous thrombolysis on neurological function, oxidative stress, and immune function in patients with acute ischemic stroke.

Yun Wang, Yang Yang, Jingmin Zhou

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yun Wang *Department of Neurology, Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an), Huai'an, Jiangsu, China.
Yang Yang *Department of Neurology, Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an), Huai'an, Jiangsu, China.
Jingmin ZhouDepartment of Neurology, Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an), Huai'an, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: This study aimed to assess the clinical efficacy of neurointerventional therapy plus intravenous thrombolysis in patients with acute ischemic stroke (AIS). Methods: We conducted a single-center retrospective analysis involving 120 AIS patients admitted to our hospital from January 2023 to December 2024. Based on their treatment plans, patients were categorized into an alteplase group ( Results: After 3 months of treatment, the combination group demonstrated significantly lower NIHSS and mRS scores, as well as reduced levels of IL-6, TNF-α, and hs-CRP, compared to the alteplase group ( Conclusion: Neurointerventional therapy plus intravenous thrombolysis can improve the neurological function, reduce inflammation and oxidative stress, enhance immune function, improve hemodynamic indicators, improve the quality of life and has good safety in the treatment of patients with AIS.

Indexed as

acute ischemic strokeimmune functionintravenous thrombolysisneurointerventional therapyneurological functionoxidative stress

Identifiers

PMID41728600
PMCPMC12916641

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.