Evidence map›Paper›PMID 41728586›Full record

ArticleACS medicinal chemistry letters2026

The Effect of

Ryan M Herrick, Samantha A Green, Sharyl Rich, Jessica M Grandner, Kim Huard, Ryan A Altman

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ryan M HerrickBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.
Samantha A GreenGenentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Sharyl RichGenentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Jessica M GrandnerGenentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Kim HuardGenentech, 1 DNA Way, South San Francisco, CA 94080, USA.
Ryan A AltmanBorch Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, IN 47907, USA.

Funding

Transgenic Mouse Core Facility Shared Resource (TMCF-SR)P30CA023168 · NCI · PURDUE UNIVERSITY WEST LAFAYETTE · PI ANDREW D MESECAR · 1985 to 2026
$43.4M
Grant Supplement to Support Diversity in Health-Related ResearchR35GM124661 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI Ryan A Altman · 2017 to 2026
$4.1M
NCI NIH HHS P30 CA023168NIGMS NIH HHS R35 GM124661
6 · The paper itself

Abstract

Despite recent interest in

Indexed as

DIFLUORINATIONFLUORINATIONHETEROCYCLESMATCHED MOLECULAR PAIRS

Identifiers

PMID41728586
PMCPMC12922629

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.