ArticleCureus2026
Global Trends in Mortality From Ischemic Heart Disease and the Expansion of Interventional Cardiology Procedures: An Analysis Using the Global Burden of Disease (GBD) Dataset.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Biomaterial-Assisted Stem Cell Therapy and Exosome Delivery in Myocardial Infarction: A Narrative Review.Biomimetics (Basel, Switzerland) · 2026Review
- Ischemic Heart Disease and the Epidemiologic Transition: Progress without Reduction in Global Burden.Discoveries (Craiova, Romania)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIschemic heart disease (IHD) remains the leading cause of global mortality, with notable regional disparities reflecting differences in healthcare access, socioeconomic status, and interventional cardiology capacity.
objectiveTo assess global and regional trends in ischemic heart disease (IHD) mortality from 2000 to 2021 using Global Burden of Disease (GBD) data across seven regions.
methodsA descriptive analytical design was applied using age-standardized IHD mortality data extracted from the GBD database for the years 2000-2021. Regional averages and percentage changes were computed to examine temporal trends.
resultsA general decline in IHD mortality was observed globally, with the most pronounced reductions in Western and Eastern Europe, moderate declines in Latin America, East Asia, and globally overall, and minimal change in Sub-Saharan Africa. South Asia showed a slight increase. The variations closely align with differences in access to interventional cardiology services and preventive cardiovascular programs.
conclusionDespite overall global improvement, persistent disparities highlight the need to strengthen interventional cardiology capacity and preventive care systems in low- and middle-income regions to achieve equitable cardiovascular outcomes.
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Registered trials
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