Evidence map›Paper›PMID 41728262›Full record

ArticleBrain communications2026

Adults with Down syndrome display altered entrainment of occipital cortical neurons.

Liana Chinen, Morgan T Busboom, Jiraros Meejang, Olyvia Kastner, Elizabeth Heinrichs-Graham, Tony W Wilson, Max J Kurz

Abstract read
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liana ChinenInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Morgan T BusboomInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Jiraros MeejangInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Olyvia KastnerInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.
Elizabeth Heinrichs-GrahamInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.ORCID https://orcid.org/0000-0002-7914-5258
Tony W WilsonInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.ORCID https://orcid.org/0000-0002-5053-8306
Max J KurzInstitute for Human Neuroscience, Boys Town National Research Hospital, Omaha, NE 68010, USA.ORCID https://orcid.org/0000-0001-7040-5474

Funding

Stress-Induced Aberrations in the Mitochondrial Redox Environment Impact Developing Neural Circuits Supporting Cognitive ControlP20GM144641 · NIGMS · FATHER FLANAGAN'S BOYS' HOME · PI Giorgia Picci · 2022 to 2026
$15.1M
New MEG System for Improved Quantification of Human Brain DynamicsS10OD028751 · OD · FATHER FLANAGAN'S BOYS' HOME · PI WILSON, TONY W · 2020 to 2020
$1.9M
NIGMS NIH HHS P20 GM144641NIH HHS S10 OD028751
6 · The paper itself

Abstract

Down syndrome is commonly associated with a trisomy of chromosome 21 that often presents an accelerated aging profile and higher probability of developing Alzheimer's disease-like symptoms at a relatively early age. However, the physiological changes that may contribute to such symptoms remain poorly understood. To begin to address this knowledge gap, we used magnetoencephalographic neurophysiological imaging to assess the entrainment of occipital cortical neurons to a 15 Hz visual stimulus in a cohort of adults with DS without a dementia diagnosis (

Indexed as

Alzheimer’s diseasedementiamagnetoencephalographyneuroimagingvision

Identifiers

PMID41728262
PMCPMC12922442

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.