Balancing Act: Lessons From Comanaging Patients With Inflammatory Bowel Disease and HIV/AIDS.

Erick Cruz Grave, Paul Paik, John Kim, Florence-Damilola Odufalu

Abstract readCase Reports

In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erick Cruz GraveDepartment of Internal Medicine, University of Southern California/Los Angeles General Medical Center, Los Angeles, CA.

Paul PaikDepartment of Internal Medicine, Division of Gastroenterology & Hepatology, Los Angeles Medical Center, Los Angeles, CA.

John KimDepartment of Internal Medicine, Division of Gastroenterology & Hepatology, Los Angeles Medical Center, Los Angeles, CA.

Florence-Damilola OdufaluDepartment of Internal Medicine, Division of Gastroenterology & Liver Diseases, University of Southern California, Los Angeles, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with inflammatory bowel disease (IBD) and human immunodeficiency virus (HIV) present unique challenges due to overlapping immune dysregulation and heightened infection risk. Although immunosuppressive therapy is central to management of moderate to severe IBD, concurrent HIV infection complicates both diagnostic evaluation and therapeutic decisions. Outcomes in this population remain poorly defined, with limited evidence available to guide management. This case series evaluates 3 challenging cases that demonstrates the diagnostic uncertainty and therapeutic complexity encountered when IBD and HIV coexist, underscoring the need for individualized, multidisciplinary care and further investigation to optimize outcomes in this vulnerable population.

Indexed as

advanced therapiesAIDSbiologic therapyHIVIBD flareinflammatory bowel disease

Identifiers

PMID41728248

DOI10.14309/crj.0000000000002001

PMCPMC12922919

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.