Evidence map›Paper›PMID 41728247›Full record

ArticleACG case reports journal2026

Duodenal Small Bowel Diaphragm Disease: A Rare and Underrecognized Complication of Chronic NSAID Use.

Idan Grossmann, Aubin Attila, Harshavardhan Sanekommu, Chinmay Trivedi, Vera Hapshy, Natasha Campbell, Lee Peng, Angelo Chinnici, Mohammad Hossain

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Idan GrossmannDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Aubin AttilaDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Harshavardhan SanekommuDivision of Gastroenterology, Jersey Shore University Medical Center, Neptune, NJ.
Chinmay TrivediDivision of Gastroenterology, Hackensack Meridian Palisades Medical Center, North Bergen, NJ.
Vera HapshyDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Natasha CampbellDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Lee PengDivision of Gastroenterology, Jersey Shore University Medical Center, Neptune, NJ.
Angelo ChinniciDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.
Mohammad HossainDepartment of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications. Although common adverse effects such as gastrointestinal bleeding, ulcers, and kidney injury are widely known, small bowel diaphragm disease, an exceedingly rare complication of long-term NSAID use, remains underrecognized. We report an uncommon case of a 56-year-old patient on long-term high-dose NSAIDs who developed diaphragm disease involving the duodenum, a rarely reported location, manifesting as intestinal obstruction. This case highlights the potential for unusual anatomical involvement to mask diagnosis and underscores the importance of early consideration of this diagnosis in patients with chronic NSAID use and unexplained obstructive presentations.

Indexed as

duodenal obstructionnonsteroidal anti-inflammatory drugs (NSAIDs)small bowel diaphragm diseasesmall bowel obstructionsmall bowel pathology

Identifiers

PMID41728247
PMCPMC12922905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.