Evidence map›Paper›PMID 41728222›Full record

ArticleEuropean heart journal. Case reports2026

Five-year histological evaluation of paclitaxel-eluting stent for an infrapopliteal lesion: a case report.

Yosuke Hata, Osamu Iida, Sho Torii, Manabu Shiozaki, Toshiaki Mano

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yosuke HataCardiovascular Center, Kansai Rosai Hospital, Hyogo, 660-8511, Japan.ORCID https://orcid.org/0000-0001-5482-3502
Osamu IidaCardiovascular Division, Osaka Keisatsu Hospital, Osaka, 543-0042, Japan.
Sho ToriiDepartment of Cardiology, Tokai University School of Medicine, Kanagawa, 259-1193, Japan.
Manabu ShiozakiDepartment of Cardiology, Tokai University School of Medicine, Kanagawa, 259-1193, Japan.
Toshiaki ManoCardiovascular Center, Kansai Rosai Hospital, Hyogo, 660-8511, Japan.ORCID https://orcid.org/0000-0002-9047-380X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The long-term vascular response to paclitaxel-eluting stents (PESs) in infrapopliteal (IP) lesions remains histologically uncharacterized. Case summary: A 78-year-old woman with chronic limb-threatening ischaemia underwent implantation of two overlapping paclitaxel-eluting stents from the tibioperoneal trunk to the peroneal artery for an ischaemic ulcer. Multimodality follow-up imaging was obtained at both 3 and 5 years, including optical frequency domain imaging (OFDI) and angioscopy performed immediately before amputation. At 3 years, OFDI and angioscopy demonstrated uncovered struts with adherent thrombus. At 5 years, OFDI and angioscopy showed mature neointima over the proximal and distal segments but persistent fibrin-coated, uncovered struts within the 40-mm overlap. Progressive ischaemia culminated in below-the-knee amputation, permitting stent explantation. Histopathology confirmed proteoglycan-rich neointima at the non-overlapped segments and delayed healing with fibrin deposition and uncovered struts confined to the overlap. Conclusion: The 5-year histological evaluation of the PES revealed paclitaxel-related impaired endothelialization in IP lesions.

Indexed as

Case reportChronic limb-threatening ischaemiaHistologyInfrapopliteal lesionNeoatherosclerosisPaclitaxel-eluting stentUncovered strut

Identifiers

PMID41728222
PMCPMC12919362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.