ArticleFrontiers in veterinary science2026
Longitudinal study of mammary microbiota dynamics and mastitis prevention in Holstein cows by dry-off strategy.
Article in Frontiers in veterinary science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Ecological Reassembly of the Milk Microbiome and Its Associated Resistome During the Dry Period in Dairy Cows.Veterinary sciences · 2026Article
- Laminitis in Holstein dairy cows is associated with intestinal and mammary dysfunction, systemic inflammation, and microbiota dysregulation.Frontiers in microbiology · 2026Article
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Authors and funding
8 authors.
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Abstract
Introduction: Conducting a dry-off period during the late lactation phase in dairy cows can reduce the incidence of clinical mastitis both during the dry period and after subsequent calving. The primary dry-off methods include the application of antibiotics alone or in combination with internal teat sealants. A thorough understanding of the mammary gland microbiota composition before and after dry-off is essential for developing scientifically sound dry-off protocols in practical dairy production. Methods: Five Holstein cows approaching dry-off were selected for this study. The day of calving is designated as Day 0. Milk samples were collected at three time points around the drying period for 16S rRNA gene sequencing to investigate the differences in mammary microbial composition during these stages. Including Group A (-95 to -67 days), Group B (1 to 2 days), and Group C (14 days). Results: The results showed that compared to Group A, the abundance of Conclusion: This exploratory study preliminarily indicates that a single dose of cefapirin benzathine administered via intramammary infusion before drying-off can effectively reduce the abundance of specific mammary pathogens, including
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