Evidence map›Paper›PMID 41728076›Full record

ArticleNanoscale advances2026

Porphyrin-coated gold nanoparticles associated with X-rays and proton therapy in the treatment of triple-negative breast cancer.

Camila Ramos Silva, Guillaume Berionni, Martha Simões Ribeiro, Anne-Catherine Heuskin

Abstract read
In one paragraph

Article in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Camila Ramos SilvaNamur Research Institute for Life Sciences (NARILIS) - University of Namur Namur Belgium anne-catherine.heuskin@unamur.be.ORCID https://orcid.org/0000-0003-2081-3319
Guillaume BerionniChemistry Department-University of Namur Namur Belgium.ORCID https://orcid.org/0000-0002-5422-9113
Martha Simões RibeiroCenter for Lasers and Applications, Energy and Nuclear Research Institute-IPEN-CNEN São Paulo Brazil.ORCID https://orcid.org/0000-0002-4203-1134
Anne-Catherine HeuskinNamur Research Institute for Life Sciences (NARILIS) - University of Namur Namur Belgium anne-catherine.heuskin@unamur.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer, known for its marked resistance to radiotherapy. Recent research has focused on developing innovative therapeutic strategies to overcome this challenge, with one promising approach being the combination of photodynamic therapy (PDT) and radiotherapy (RT). However, the potential of nanoparticles loaded with photosensitizers to enhance therapeutic efficacy, particularly in combination with charged particle therapies, such as proton therapy (PT), remains underexplored. In this study, we developed porphyrin-coated gold nanoparticles (AuNPs@TMPyP) to integrate PDT with RT using both photons and protons. PDT was performed using AuNPs@TMPyP (35 µg mL

Identifiers

PMID41728076
PMCPMC12921571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.