Evidence map›Paper›PMID 41727961›Full record

ArticleJournal of translational internal medicine2026

Methyltransferase like 3 promotes thyroid folliculogenesis

Ruoyu Jiang, Qibo Zhu, Zhenlei Zhang, Xiao He, Yifan Liu, Ronglin Kan, Xianghui He, Haixia Guan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of translational internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruoyu JiangDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.
Qibo ZhuDepartment of Endocrinology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong Province, China.
Zhenlei ZhangDepartment of Thyroid and Neck Oncology, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Immune Microenvironment and Disease, Tianjin, China.
Xiao HeDepartment of Thyroid and Neck Oncology, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Immune Microenvironment and Disease, Tianjin, China.
Yifan LiuDepartment of Thyroid and Neck Oncology, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Immune Microenvironment and Disease, Tianjin, China.
Ronglin KanDepartment of Thyroid and Neck Oncology, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Immune Microenvironment and Disease, Tianjin, China.
Xianghui HeDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, Tianjin, China.ORCID https://orcid.org/0000-0001-9977-162X
Haixia GuanDepartment of Endocrinology, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, Guangdong Province, China.ORCID https://orcid.org/0000-0003-3155-2847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder with largely elusive underlying mechanisms, although thyroid dysformation has been deemed as the most frequent cause. Methyltransferase like 3 (METTL3) serves as a pivotal writer for N Methods: Thyrocyte-specific Results: Thyrocyte specific removal of Conclusions:

Indexed as

cell differentiationcell polaritycongenital hypothyroidismMETTL3

Identifiers

PMID41727961
PMCPMC12916267

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.