Evidence map›Paper›PMID 41727928›Full record

ReviewO&G open2026

Uterine Tachysystole and Associated Outcomes: A Systematic Review and Meta-analysis.

Fabrizio Zullo, Benedetta Licitra, Nandini Raghuraman, Alison G Cahill, Aaron W Roberts, Stephanie Roth, Daniele Di Mascio, Antonella Giancotti, Giuseppe Rizzo, Kristen A Cagino and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in O&G open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fabrizio ZulloDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Benedetta LicitraDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Nandini RaghuramanDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Alison G CahillDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Aaron W RobertsDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Stephanie RothDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Daniele Di MascioDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Antonella GiancottiDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Giuseppe RizzoDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Kristen A CaginoDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Hector Mendez-FigueroaDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Anthony C SciscioneDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.
Suneet P ChauhanDepartment of Maternal and Child Health and Urological Sciences, Sapienza University of Rome, Rome, Italy; Department of Obstetrics and Gynecology and Medical Libraries, ChristianaCare Health System, Newark, Delaware; Division of Maternal-Fetal Medicine, Washington University at St. Louis, St. Louis, Missouri; Department of Women's Health, University of Texas at Austin, Dell Medical School, Austin, Texas; Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; and Delaware Center for Maternal Fetal Medicine of ChristianaCare, Newark, Delaware.

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUM1TR004538 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ROBERT A CLARK, Kenneth M Hargreaves · 2023 to 2026
$22.3M
NCATS NIH HHS UM1 TR004538
6 · The paper itself

Abstract

objectiveTo determine whether uterine tachysystole is associated with adverse neonatal and maternal outcomes. DATA SOURCES: A search strategy for PubMed (National Library of Medicine) was created, and the medical librarian translated the search for every database. The search strategy was peer reviewed by another medical librarian following the Peer Review of Electronic Search Strategies checklist. The databases included in this search were PubMed, Embase.com, Cochrane CENTRAL, CINAHL Ultimate, and Scopus; a combination of key words and subject headings was used. METHODS OF STUDY SELECTION: Trials of nulliparous or multiparous parturients exposed to uterine tachysystole were included. Included studies compared individuals with and those without uterine tachysystole. TABULATION INTEGRATION AND

resultsTwo reviewers independently extracted data and assessed risk of bias. Random-effect head-to-head meta-analyses reporting summary odds ratios (ORs) with 95% CIs were performed. The random-effects model of DerSimonian and Laird was used. Values of

conclusionObservational studies do not report significant differences in the likelihood of adverse neonatal outcomes and cesarean delivery among individuals exposed compared with those not exposed to uterine tachysystole during labor. Additional data, from either interventional trials or observational studies with better characterization of the interventions and outcomes, on uterine tachysystole and adverse outcomes are needed. SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42024560155.

Identifiers

PMID41727928
PMCPMC12922903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.