Evidence map›Paper›PMID 41727713›Full record

ArticleVirus evolution2026

The whole genome analysis of four Orf virus strains from Europe and South America.

Marco Cacciabue, Laura C Lozano Calderón, Javier Moleres, Irache Echeverría, Lorena de Pablo, Idoia Glaria, Guido König, Andrea Peralta, Ramsés Reina

Abstract read
In one paragraph

Article in Virus evolution, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marco CacciabueDepartamento de Ciencias Básicas, Universidad Nacional de Luján, Luján, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-1429-4252
Laura C Lozano CalderónInstituto de Agrobiotecnología y Biología Molecular (IABiMo), Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Javier MoleresInstituto de Agrobiotecnología, (CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain.
Irache EcheverríaInstituto de Agrobiotecnología, (CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain.
Lorena de PabloInstituto de Agrobiotecnología, (CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain.
Idoia GlariaInstituto de Agrobiotecnología, (CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain.
Guido KönigInstituto de Agrobiotecnología y Biología Molecular (IABiMo), Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Andrea PeraltaInstituto de Agrobiotecnología y Biología Molecular (IABiMo), Instituto Nacional de Tecnología Agropecuaria (INTA), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Hurlingham, Buenos Aires, Argentina.
Ramsés ReinaInstituto de Agrobiotecnología, (CSIC-Gobierno de Navarra), Avda. Pamplona 123, 31192 Mutilva, Navarra, Spain.ORCID https://orcid.org/0000-0003-1265-9139

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orf virus (ORFV) is the etiological agent of Contagious Ecthyma, a global disease that mainly affects sheep, goats, wild ruminants, and humans. Here, we determined the complete genome sequence of two ORFV strains from Spain (NAV and ARA) and two from Argentina (HRE and CHB), representing the first report from the Iberian Peninsula and from South America. The assembled genomes of the ARA, CHB, HRE, and NAV strains of ORFV were found to be 137 891 , 137 160, 137 340, and 137 214 bp long, respectively, each contained 132 genes, and all showed high amino-acid identity and similar lengths compared to the reference strain NZ2. We performed a microsatellite analysis to identify molecular signatures associated with host species (sheep or goat). In addition, the analysis of 32 selected genes showed that the median nucleotide substitution rate for the worldwide cluster 3 that includes the four samples described in this study, was 2.6 x10

Indexed as

genomic sequencingORFVparapoxvirusphylogenetic analysis

Identifiers

PMID41727713
PMCPMC12922540

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.