ArticleFrontiers in oncology2026
Case Report: A rare case of breast leiomyoma with literature review.
Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast leiomyoma is a rare benign mesenchymal tumor that typically manifests as a solitary, slow-growing mass. This article presents a case of a 58-year-old female with a history of follicular lymphoma confirmed by pathological examination of resected lymph nodes in November 2019. Follow-up positron emission tomography/computed tomography (PET-CT) revealed a breast soft-tissue mass initially classified as likely benign. Subsequent chest computed tomography (CT) in May 2024 demonstrated enlargement of the lesion, raising suspicion of lymphomatous infiltration. The mammogram shows an irregular mass shadow with shallow lobulation and scattered punctate and coarse calcification shadows. It is classified as BI-RADS 4b. Multimodal ultrasound evaluation (including grayscale ultrasound, color doppler, shear-wave elastography, strain elastography, and contrast-enhanced ultrasound) identified a solid breast mass categorized as BI-RADS 4b. Ultrasound-guided core needle biopsy revealed adenosis with focal fibroadenomatoid changes. Definitive diagnosis was achieved through surgical excision, with histopathology demonstrating fascicular arrangements of spindle-shaped smooth muscle cells on hematoxylin-eosin staining, corroborated by immunohistochemical confirmation (SMA+/desmin+). Postoperative surveillance at 6 months showed no recurrence. A search was conducted in the PubMed database using "breast leiomyoma" as the keyword, with the publication date limited to January 1, 2015, to May 3, 2025. A total of 192 articles were retrieved. After applying rigorous selection criteria, 11 case reports that met the criteria were finally included for systematic review, involving a total of 12 cases of pathologically confirmed breast leiomyoma (one report contained 2 cases). Notably, only one study comprehensively characterized the contrast-enhanced ultrasound features, and no elastography examination was performed in any of the cases. This report presents a case of breast leiomyoma in a patient with a history of lymphoma. The imaging features were highly suggestive of malignancy, yet histopathological examination confirmed a benign lesion. This study aims to analyze the clinical and preoperative imaging characteristics of this case. Combined with a comprehensive literature review, it thoroughly explores the diagnostic imaging manifestations of breast leiomyoma, providing a reference for clinical differential diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.