Evidence map›Paper›PMID 41727372›Full record

ArticleACS measurement science au2026

Dual Ionization Ion-Mobility Mass Spectrometry Hyphenated with Catalytic Oxygenation-Mediated Extraction.

Tzu-Ching Tsai, Chamarthi Maheswar Raju, Pawel L Urban

Abstract read
In one paragraph

Article in ACS measurement science au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tzu-Ching TsaiDepartment of Chemistry, National Tsing Hua University, 101 Section 2 Kuang-Fu Rd, Hsinchu 300044, Taiwan.
Chamarthi Maheswar RajuDepartment of Chemistry, National Tsing Hua University, 101 Section 2 Kuang-Fu Rd, Hsinchu 300044, Taiwan.
Pawel L UrbanDepartment of Chemistry, National Tsing Hua University, 101 Section 2 Kuang-Fu Rd, Hsinchu 300044, Taiwan.ORCID https://orcid.org/0000-0003-3471-045X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catalytic oxygenation-mediated extraction (COME) is an environmentally friendly liquid-gas extraction technique that generates oxygen microbubbles via the catalytic decomposition of hydrogen peroxide. While corona discharge atmospheric pressure chemical ionization (APCI) is widely used for analyzing moderately polar and lower-polarity analytes with low molecular weights, secondary electrospray ionization (SESI) is a soft ionization technique that effectively ionizes polar volatile analytes. This study aims to integrate APCI and SESI with COME drift-tube ion-mobility (IM) triple quadrupole mass spectrometry (MS) to analyze volatile organic compounds (VOCs) with different physicochemical properties present in liquid matrices. The coupling of a house-built ion-mobility spectrometer with a commercial triple quadrupole mass spectrometer provides 2D separation at low cost. The user can choose one of the two ionization modes to achieve high signals with VOCs of different polarity. COME was applied to extract ethyl acetate from complex matrices (Taiwanese millet wine and whiskey) for immediate IM-MS analysis. An isotopically labeled internal standard was used to compensate for drift time and intensity shifts across multiple analyses. The system operates automatically with a graphical user interface enabling immediate ion-mobility spectrum visualization for targeted

Indexed as

atmospheric pressure chemical ionizationgreen analytical chemistryionization methodsion-mobility spectrometrysample preparationsecondary electrospray ionizationvolatile organic compounds

Identifiers

PMID41727372
PMCPMC12921609

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.