ArticleNature reviews. Methods primers2025
In vivo microelectrode arrays for neuroscience.
Article in Nature reviews. Methods primers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- High-channel-count neural recording and stimulation platform with 5376 simultaneous recording channels.npj biomedical innovations · 2026Article
- CASCADE: criticality avalanche spike cross-platform analysis detection engine, a multi-manufacturer MEA bash analysis pipeline.Bioinformatics (Oxford, England) · 2026Article
- Inkjet-Printed Rough Gold Microelectrode Arrays on Flexible Substrates for Neural Recording and Electrical Stimulation.ACS applied materials & interfaces · 2026Article
- Hands-free control of an assistive robotic arm for high-level paralysis.Journal of neuroengineering and rehabilitation · 2026Article
- Highly mechanically stable PEDOT:PSS/PDA-modified microelectrode arrays reveal state-specific dynamic neural activity across sleep-wake.Microsystems & nanoengineering · 2026Article
- High-channel-count neural recording and stimulation platform with 5,376 simultaneous recording channels.bioRxiv : the preprint server for biology · 2026Article
- Revealing spatiotemporal neural activation patterns in electrocorticography recordings of human speech production by mutual information.Neuroscience informatics · 2025Article
- Electroanatomy of hippocampal activity patterns: theta, gamma waves, sharp wave-ripples, and dentate spikes.Frontiers in behavioral neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Microelectrode arrays (MEAs) are devices capable of recording extracellular action potentials (spikes) from many neurons simultaneously and with high spatial and temporal resolution. MEAs have emerged as an invaluable tool for understanding how networks of neurons govern complex sensory, motor and decision-making processes. In this Primer, we introduce various in vivo MEA designs and describe their construction, characterization and applications. We describe approaches for effective device implantation and the use of MEA recordings in behavioural experiments. We then discuss strategies for obtaining high-quality and stable electrophysiological recordings, including through mitigating the foreign body reaction. We introduce the reader to spike sorting approaches with a focus on semi-automated sorting of high-channel-count data, as well as to the analysis of sorted spikes and their uses. Finally, we cover future trends and emerging MEA technology designed to expand current capabilities and overcome limitations, with a focus on biomimetic and multifunctional devices. This Primer should provide the reader with a foundation in the fundamental principles of MEA technology for in vivo use.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.