Evidence map›Paper›PMID 41727189›Full record

ArticleiScience2026

Reduced

Keishiro Isayama, Kenji Watanabe, Masato Ohtsuka, Seisuke Kimura, Tomoaki Murata, Takeshi Honda, Masataka Asagiri, Shun Sato, Hiroshi Tamura, Norihiro Sugino and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Keishiro IsayamaInstitute of Gene Research, Yamaguchi University Science Research Center, Yamaguchi 755-8505, Japan.
Kenji WatanabeInstitute of Gene Research, Yamaguchi University Science Research Center, Yamaguchi 755-8505, Japan.
Masato OhtsukaDepartment of Molecular Life Science, Division of Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Seisuke KimuraDepartment of Industrial Life Sciences, Faculty of Life Sciences, Kyoto Sangyo University, Kita-ku, Kyoto 603-8555, Japan.
Tomoaki MurataInstitute of Life Science and Medicine, Yamaguchi University Science Research Center, Yamaguchi 755-8505, Japan.
Takeshi HondaDepartment of Pharmacology, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Masataka AsagiriDepartment of Pharmacology, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Shun SatoDepartment of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Hiroshi TamuraDepartment of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Norihiro SuginoDepartment of Obstetrics and Gynecology, Yamaguchi University Graduate School of Medicine, Yamaguchi 755-8505, Japan.
Yoichi MizukamiInstitute of Gene Research, Yamaguchi University Science Research Center, Yamaguchi 755-8505, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural ovarian aging is associated with a progressive decline in female fertility. Here, we comprehensively analyzed RNA expression during ovarian aging in mice during the estrous cycle following ovulation stimulation. The transient activation of the Aldo-keto reductase

Indexed as

Endocrine regulationEndocrine system physiologyEndocrinologyFemale reproductive endocrinologyHealth sciences

Identifiers

PMID41727189
PMCPMC12918200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.