Evidence map›Paper›PMID 41727126›Full record

ArticlebioRxiv : the preprint server for biology2026

Type I interferon signaling promotes early innate control of

Raj Priya, Sajith Raghunandanan, Darco Mihaljica, Nada S Alakhras, Mark H Kaplan, X Frank Yang

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raj PriyaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Sajith RaghunandananDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Darco MihaljicaDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Nada S AlakhrasDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Mark H KaplanDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
X Frank YangDepartment of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.ORCID 0000-0002-7231-3167

Funding

Regulatory Network of the Lyme Disease PathogenR01AI083640 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI X. Frank Yang · 2009 to 2026
$5.9M
Targeting Cyclic Dinucleotide Signaling Pathways to Interrupt the Nature Cycle of Borrelia burgdorferiR01AI152235 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SINTIM, HERMAN O, YANG, X. FRANK · 2020 to 2024
$3.4M
NIAID NIH HHS R01 AI083640NIAID NIH HHS R01 AI152235
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41727126
PMCPMC12918912

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.