Evidence map›Paper›PMID 41727118›Full record

ArticlebioRxiv : the preprint server for biology2026

Input-and cell-type-specific developmental alterations to thalamic synapses in a Dravet syndrome mouse model.

Mona Safari, Rutvi Desai, Harbal Rai, Tyler J Roberts, Rabeya Khondaker, Julia Smith, Sharon A Swanger

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona SafariFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Rutvi DesaiFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Harbal RaiFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Tyler J RobertsFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Rabeya KhondakerFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Julia SmithFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.
Sharon A SwangerFralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA.ORCID 0000-0003-0615-6244

Funding

Molecular and functional diversity of NMDA receptors in the thalamusR01NS105804 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SWANGER, SHARON ANN · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS105804
6 · The paper itself

Abstract

Dravet syndrome is an epileptic encephalopathy most often caused by loss-of-function mutations in the

Indexed as

corticothalamicDravet syndromeNaV1.1SCN1Asomatosensorysynapse developmentthalamus

Identifiers

PMID41727118
PMCPMC12918865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.