Evidence map›Paper›PMID 41727117›Full record

ArticlebioRxiv : the preprint server for biology2026

Metaplastic neuronal state transition regulates species-specific interoceptive processing in

Adam M Brann, Dieu Linh Nguyen, Alexa N Zarjetskiy, Natalia Pokaleva, Elizabeth M Paul, Masashi Tabuchi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam M BrannDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Dieu Linh NguyenDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Alexa N ZarjetskiyDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Natalia PokalevaDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Elizabeth M PaulDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Masashi TabuchiDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH, United States.ORCID 0000-0002-8734-6922

Funding

The role of non-canonical neural codes in behaviorR35GM142490 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Masashi Tabuchi · 2021 to 2026
$2.6M
Mechanisms mediating the relationship between temporal coding and sleepR00NS101065 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI TABUCHI, MASASHI · 2020 to 2022
$737k
NIGMS NIH HHS R35 GM142490NINDS NIH HHS R00 NS101065
6 · The paper itself

Abstract

Interoceptive processing, which involves the sensing and integration of internal physiological states, is fundamental to maintaining homeostasis. However, how species-specific interoceptive features arise from the underlying biophysical properties of neural circuit physiology remains unclear. We investigate the biophysical basis of species-specific interoception by examining protein-hunger dopamine neurons (DA-WED) in two

Indexed as

DrosophilaInteroceptionMetaplasticityNeural state transitionsProtein-deprivation response

Identifiers

PMID41727117
PMCPMC12919059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.