Evidence map›Paper›PMID 41727031›Full record

ArticlebioRxiv : the preprint server for biology2026

Expanding CyanoHAB Monitoring: New Micropeptins and Generalizable MS/MS Workflows for the Annotation of Cyanopeptide Classes.

Runjie Xia, Lindsey Ahn, Michaela Burkhauser, Ross Youngs, Matthew J Bertin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Runjie XiaDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
Lindsey AhnDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
Michaela BurkhauserDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.
Ross YoungsBiosortia, Inc., 2545 Farmers Dr., Suite 370, Columbus, OH 43235, United States.ORCID 0009-0009-7422-8378
Matthew J BertinDepartment of Chemistry, Case Western Reserve University, Cleveland, OH 44106, United States.ORCID 0000-0002-2200-0277

Funding

Shifting paradigms to emerging toxins in freshwater cyanobacterial bloomsR21ES033758 · NIEHS · UNIVERSITY OF RHODE ISLAND · PI BERTIN, MATTHEW JOHN · 2022 to 2023
$415k
NIEHS NIH HHS R21 ES033758
6 · The paper itself

Abstract

Cyanobacterial harmful algal blooms (cyanoHABs) are a major ecological and public health concern, commonly monitored for hepatotoxic microcystins and cylindrospermopsins and neurotoxic anatoxins and saxitoxins. However, the broader suite of bioactive metabolites produced during blooms remains under characterized. Here, we interrogated a chromatography fraction library generated from a cyanoHAB in Muskegon, Michigan. From this library, we isolated two new micropeptins (

Indexed as

cyanoHABscyanopeptidesLC-MS/MSmicropeptinsprotease inhibition

Identifiers

PMID41727031
PMCPMC12918887

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.