Evidence map›Paper›PMID 41726961›Full record

ArticlebioRxiv : the preprint server for biology2026

Affiliation in mice induced by an auditory-conditioned stimulus.

Wataru Ito, Alexei Morozov

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Wataru ItoFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA.
Alexei MorozovFralin Biomedical Research Institute at Virginia Tech Carilion, Roanoke, VA, USA.ORCID 0000-0003-0495-3987

Funding

Sex Difference in the Integration of Visual Social Stimulus and Emotional Auditory StimulusR21MH137592 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MOROZOV, ALEXEI · 2024 to 2025
$440k
NIMH NIH HHS R21 MH137592
6 · The paper itself

Abstract

Social affiliation is a vital survival strategy that promotes well-being across species. While innate threats consistently trigger affiliation, it remains unclear whether learned threats engage the same affiliative systems. Here, we report that an auditory conditioned stimulus induced affiliation in mice. In same-sex dyads, mice subjected to auditory fear conditioning increased proximity during presentation of the conditioned stimulus (CS). This CS-evoked affiliation was independent of freezing levels, required familiarity between partners, and depended on intact basolateral amygdala-to-ventral hippocampus inputs and oxytocin signaling. These findings suggest that neural pathways activated by learned and innate threats converge on shared social-affiliation circuitry.

Indexed as

affiliationamygdalafear conditioninghippocampusmouseoxytocinthreat

Identifiers

PMID41726961
PMCPMC12918960

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.