Evidence map›Paper›PMID 41726955›Full record

ArticlebioRxiv : the preprint server for biology2026

Septins associate with AP-3 to support trafficking to the vacuole/lysosome in yeast.

Mitchell Leih, Michaela McCright, Cortney Angers, Michael Davey, Elizabeth Conibear, Alex Merz, Greg Odorizzi

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Mitchell LeihDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0000-0002-5927-6154
Michaela McCrightDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0009-0007-7806-2366
Cortney AngersDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Michael DaveyDepartment of Medical Genetics, University of British Columbia, Vancouver, BC VH6 3N1, Canada.ORCID 0000-0002-1172-5934
Elizabeth ConibearDepartment of Medical Genetics, University of British Columbia, Vancouver, BC VH6 3N1, Canada.ORCID 0000-0001-5129-0499
Alex MerzDepartment of Biochemistry, University of Washington, Seattle, WA 98195.ORCID 0000-0003-2177-6492
Greg OdorizziDepartment of Molecular Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309.ORCID 0000-0002-1143-1098

Funding

ZDS2P REGULATES SWE1P-DEPENDENT POLARIZED CELL GROWTH IN S CEREVISIAEP41RR011823 · NCRR · UNIVERSITY OF WASHINGTON · PI YATES III, JOHN R · 1996 to 2011
$24.7M
Membrane trafficking to lysosomeshttps://apps.era.nih.gov/gmii/manage/view.era?applId=11030651#R35GM149202 · NIGMS · UNIVERSITY OF COLORADO · PI CHARLES G ODORIZZI · 2023 to 2026
$2.2M
NCRR NIH HHS P41 RR011823NIGMS NIH HHS R35 GM149202
6 · The paper itself

Abstract

Adaptor protein complex 3 (AP-3) mediates clathrin-independent transport to lysosomes, yet accessory factors supporting this pathway remain incompletely defined. In

Indexed as

Adaptor protein complexBimolecular fluorescence complementationGolgiLysosomeMembrane traffickingSeptinVacuole

Identifiers

PMID41726955
PMCPMC12919031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.