In one paragraphArticle in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Eddie-Williams OwireduDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0003-4499-0678 Ashley J DenslowDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0009-0001-9997-0765 Suki ChenDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Betty MousseauDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Jeremy B FooteDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-6621-6096 Guang YangDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-6103-8836 Jessica N PeelDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-1894-8882 Rebecca BurnhamDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0009-0002-4426-8757 Kelsey BrowningDepartment of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, 35294 USA.ORCID 0009-0009-6267-0492 Troy D RandallDepartment of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, 35294 USA.ORCID 0000-0003-0643-0311 Esther Zumaquero-MartinezDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-7631-7114 Frances E LundDepartment of Microbiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0003-3083-1246 Funding
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9MVirology CoreP30AI027767 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul A. Goepfert · 1988 to 2026
$84.1MRegulation of Pathogenic Plasma Cells in Human SLEP01AI125180 · NIAID · EMORY UNIVERSITY · PI Ignacio E. Sanz · 2016 to 2026
$28.2MMolecular Analysis and Lineage Tracing of Influenza-Specific, Lung-Resident Memory B CellsR01AI152476 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2020 to 2025
$5.5MTLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signalsR01AI153365 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2020 to 2024
$3.6MControl of B cell differentiation by IFNg induced transcription factorsR01AI110508 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LUND, FRANCES E. · 2014 to 2024
$2.5MOrigin and Function of Double Negative T cells in LupusR01AI150664 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2021 to 2025
$2.3MDeveloping and Improving Institutional Animal ResourcesG20RR022807 · NCRR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CARTNER, SAMUEL CORBIN · 2006 to 2006
$647kMulti-parameter, analytic flow cytometerS10OD032296 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2022 to 2022
$464kIDENTIFICATION OF B. ANTRACIS SPORE-SURFACE PROTEINSR21AI053365 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI DRIKS, ADAM · 2002 to 2003
$444kNCI NIH HHS P30 CA013148NCRR NIH HHS G20 RR022807NIAID NIH HHS P01 AI125180NIAID NIH HHS P30 AI027767NIAID NIH HHS R01 AI110508NIAID NIH HHS R01 AI150664NIAID NIH HHS R01 AI152476NIAID NIH HHS R01 AI153365NIAID NIH HHS R21 AI053365NIH HHS S10 OD032296
6 · The paper itselfAbstract
Interferon regulatory factor 1 (IRF1), a transcription factor encoded within the 5q31 locus harboring systemic lupus erythematosus (SLE) associated variants, promotes inflammatory responses by T and myeloid cells. Although IFNγ-activated B cells also express IRF1, its role in B cell biology and SLE is unclear. Here, we use a mouse SLE model, single-cell multiomics, and human B cells to show that IRF1 intrinsically regulates
Indexed as
autoimmunityB cellsIrf1Irf4Irf8systemic lupus erythematosus
Identifiers
PMID41726941
PMCPMC12919013
What OpenQuestion holds
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LicenceCC BY-NC-ND
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