Evidence map›Paper›PMID 41726923›Full record

ArticlebioRxiv : the preprint server for biology2026

External validation and time-stability analysis of STARE, a blood-free quantification tool for irreversible PET tracers.

Gjertrud L Laurell, Elizabeth A Bartlett, Mike Schmidt, Sergey Anishchenko, Ilia Shkolnik, R Todd Ogden, J John Mann, David Beylin, Jeffrey M Miller, Francesca Zanderigo

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gjertrud L LaurellMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0003-1002-0155
Elizabeth A BartlettMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0002-9174-9951
Mike SchmidtMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0003-4721-1457
Sergey AnishchenkoBrain Biosciences, Inc., Rockville, Maryland.
Ilia ShkolnikBrain Biosciences, Inc., Rockville, Maryland.
R Todd OgdenMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.
J John MannMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0002-0265-6586
David BeylinBrain Biosciences, Inc., Rockville, Maryland.
Jeffrey M MillerMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0002-2206-9311
Francesca ZanderigoMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, New York.ORCID 0000-0001-6510-0676

Funding

Noninvasive Quantification of Brain Glucose Metabolism Using a Portable Positron Emission Tomography Camera.R01EB026481 · NIBIB · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI ZANDERIGO, FRANCESCA · 2018 to 2021
$1.8M
NIBIB NIH HHS R01 EB026481
6 · The paper itself

Abstract

Rationale: "Gold standard" blood-based quantification of dynamic Methods: Performance was assessed by comparing regional net influx rates (K Results: STARE demonstrated high correlation with Patlak K Conclusion: STARE is a viable, noninvasive alternative to traditional blood-based quantification of dynamic

Indexed as

blood-free quantificationhuman dynamic brain imagingnet influx rateportable PETtime-stability analysis

Identifiers

PMID41726923
PMCPMC12918944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.