Evidence map›Paper›PMID 41726904›Full record

ArticlebioRxiv : the preprint server for biology2026

Serpin-Driven Green Camouflage and NIR Fluorescence in Frogs.

Ravichandran Vignesh, Tri Vu, Grace Harvey, Luca Menozzi, Jesse Delia, William White, Pohan Lin, Erini Galatis, Sönke Johnsen, Junjie Yao and 1 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Ravichandran VigneshDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Tri VuStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA.
Grace HarveyDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Luca MenozziStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA.
Jesse DeliaAmerican Museum of Natural History, New York City, NY, USA.
William WhiteDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Pohan LinDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Erini GalatisDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Sönke JohnsenDepartment of Biology, Duke University, Durham, NC, USA.
Junjie YaoStephenson School of Biomedical Engineering, University of Oklahoma, Norman, OK, USA.
Carlos TaboadaDepartment of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

Funding

INNOVATIONS IN SHOCK WAVE LITHOTRIPSY TECHNOLOGYR01DK052985 · NIDDK · DUKE UNIVERSITY · PI ZHONG, PEI · 1997 to 2025
$6.1M
High-resolution High-speed Photoacoustic and Ultrasound Imaging of SmallVessel Functions in Ischemic StrokeR01NS111039 · NINDS · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2023
$2.7M
Head-mounted Photoacoustic Imaging of Deep-brain Neural Activities in Freely Behaving AnimalsRF1NS115581 · NINDS · DUKE UNIVERSITY · PI VERKHUSHA, VLADISLAV, YAO, JUNJIE · 2020 to 2020
$2.0M
High-Throughput Volumetric Photoacoustic Imaging of Living Vascularized OrganoidsR01EB028143 · NIBIB · DUKE UNIVERSITY · PI YAO, JUNJIE · 2019 to 2022
$2.0M
3D real-time super-resolution cavitation mapping in laser lithotripsy of urinary stone diseaseR01DK139109 · NIDDK · DUKE UNIVERSITY · PI Michael E Lipkin, Junjie Yao · 2024 to 2026
$1.8M
NIBIB NIH HHS R01 EB028143NIDDK NIH HHS R01 DK052985NIDDK NIH HHS R01 DK139109NINDS NIH HHS R01 NS111039NINDS NIH HHS RF1 NS115581
6 · The paper itself

Abstract

Animals have evolved multiple strategies to generate optical traits and coloration. While most amphibians rely on a three-dimensional arrangement of chromatophores in the skin, hundreds of arboreal frog species achieve leaf-like green color through a different mechanism involving reduced pigmentation, subcutaneous biological mirrors, and high concentrations of the blood-derived pigment biliverdin. Although biliverdin is rapidly excreted in most vertebrates, hylid and centrolenid frogs can retain it through the binding to a serpin-family protein (BBS). Here we show that BBSs bind biliverdin with high affinity (K

Identifiers

PMID41726904
PMCPMC12918828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.