Evidence map›Paper›PMID 41726851›Full record

ArticleEuropean urology open science2026

Evaluation of the Transition from Holmium:YAG to Pulsed Thulium:YAG for Laser Endoscopic Enucleation of the Prostate and the Effect on Procedural Performance.

Maximilian Glienke, Maximilian Ferry von Bargen, Arif Özkan, Martin Schönthaler, Konrad Wilhelm, Christian Gratzke, Arkadiusz Miernik

Abstract read
In one paragraph

Article in European urology open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maximilian GlienkeDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Maximilian Ferry von BargenDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Arif ÖzkanDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Martin SchönthalerDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Konrad WilhelmDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Christian GratzkeDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Arkadiusz MiernikDepartment of Urology, University of Freiburg Medical Center, Freiburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Endoscopic enucleation of the prostate (EEP) using holmium:YAG laser (HoLEP) is widely regarded as the surgical gold standard for surgical management of benign prostatic hyperplasia. EEP with a pulsed thulium:YAG laser (ThuLEP) has emerged as an alternative with distinct physical properties that may influence surgical performance. However, evidence on the real-world impact of switching between laser platforms remains limited. Methods: In this retrospective single-center study, we analyzed 2688 consecutive EEP procedures performed between 2015 and 2025. Three high-volume surgeons transitioned from HoLEP ( Key findings and limitations: Baseline parameters were comparable between the HoLEP and ThuLEP groups. ThuLEP was associated with significantly lower incidence of postoperative urinary retention (5.6% vs 9.3%; Conclusions and clinical implications: A transition from HoLEP to ThuLEP with a pulsed thulium:YAG laser is safe and feasible in experienced hands. ThuLEP was associated with higher enucleation efficiency and a statistically significant improvement in hemostatic control, without an increase in complication rates. These findings highlight the procedural adaptability of laser EEP techniques and support the clinical viability of platform switching in high-volume settings. Patient summary: We looked at outcomes in >2600 patients who underwent prostate surgery using two different laser systems. After switching from a holmium laser to a thulium laser, surgeons performed procedures more efficiently and with fewer cases of urinary retention and bleeding. This suggests that experienced surgeons can safely switch to newer laser systems without compromising patient care.

Indexed as

Benign prostatic hyperplasiaHolmium laserLaser enucleation of the prostatePulsed thulium laserSurgical transition

Identifiers

PMID41726851
PMCPMC12924173

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.